Proportional Reasoning

2016 ◽  
Vol 224 (4) ◽  
pp. 266-276 ◽  
Author(s):  
Ruth Stavy ◽  
Reuven Babai ◽  
Arava Y. Kallai

Abstract. Comparison of ratios is difficult for children and adults. We studied the role of salience and congruity in comparison of ratios using reaction time and functional magnetic resonance imaging (fMRI). Participants were asked to decide which of two mixtures of red and white paint drops (presented in Arabic numerals) was darker. In congruent trials the mixture with more red drops was darker and in incongruent trials it was lighter. Half of the trials were red salience (more red than white drops in both mixtures) and half of them were white salience. Interaction between congruity and salience was observed. Behaviorally, accuracy was higher and reaction time of correct responses (RTC) was shorter in congruent red salience and incongruent white salience conditions. For these conditions higher activation in a fronto-parietal numerical network was observed in fMRI. These findings suggest that automatic processing of natural numbers supports or suppresses the comparison of ratios as a function of congruity and salience.

1999 ◽  
Vol 19 (12) ◽  
pp. 1365-1375 ◽  
Author(s):  
Isabelle Loubinoux ◽  
Keder Boulanouar ◽  
Jean-Philippe Ranjeva ◽  
Christophe Carel ◽  
Isabelle Berry ◽  
...  

Fluoxetine inhibits the reuptake of serotonin, and dextroamphetamine enhances presynaptic release of monoamines. Although the excitatory effect of both noradrenaline and dopamine on motor behavior generally is accepted, the role of serotonin on motor output is under debate. In the current investigation, the authors evidenced a putative role of monoamines and, more specifically, of serotonin in the regulation of cerebral motor activity in healthy subjects. The effects on cerebral motor activity of a single dose of fluoxetine (20 mg), an inhibitor of serotonin reuptake, and fenozolone (20 mg/50 kg), an amphetamine-like drug, were assessed by functional magnetic resonance imaging. Subjects performed sensorimotor tasks with the right hand. Functional magnetic resonance imaging studies were performed in two sessions on two different days. The first session, with two scan experiments separated by 5 hours without any drug administration, served as time-effect control. A second, similar session but with drug administration after the first scan assessed drug effects. A large increase in evoked signal intensity occurred in the ipsilateral cerebellum, and a parallel, large reduction occurred in primary and secondary motor cortices (P < 10–3). These results are consistent with the known effects of habituation. Both drugs elicited comparable effects, that is, a more focused activation in the contralateral sensorimotor area, a greater involvement of posterior supplementary motor area, and a widespread decrease of bilateral cerebellar activation (P < 10–3). The authors demonstrated for the first time that cerebral motor activity can be modulated by a single dose of fluoxetine or fenozolone in healthy subjects. Drug effects demonstrated a direct or indirect involvement of monoamines and serotonin in the facilitation of cerebral motor activity.


2008 ◽  
Vol 32 (3) ◽  
pp. 347-352 ◽  
Author(s):  
Josephina A. Vossen ◽  
Ihab R. Kamel ◽  
Manon Buijs ◽  
Eleni Liapi ◽  
Christos S. Georgiades ◽  
...  

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