Serum immunoglobulin E, IgA, and IgG antibodies to different cow's milk proteins in children with cow's milk allergy: Association with prognosis and clinical manifestations

2002 ◽  
Vol 13 (4) ◽  
pp. 255-261 ◽  
Author(s):  
Edit Hidvegi ◽  
Endre Cserhati ◽  
Erzsebet Kereki ◽  
Erkki Savilahti ◽  
Andras Arato
Keyword(s):  
Immunoglobulin E ◽  
Clinical Manifestations ◽  
Milk Proteins ◽  
Cow’S Milk Allergy ◽  
Serum Immunoglobulin ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Igg Antibodies ◽  
Cow's Milk ◽  
Cow’S Milk Proteins

scholarly journals Role of Cellular Immunity in Cow’s Milk Allergy: Pathogenesis, Tolerance Induction, and Beyond

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Juandy Jo ◽  
Johan Garssen ◽  
Leon Knippels ◽  
Elena Sandalova
Keyword(s):  
Cellular Immunity ◽  
Tolerance Induction ◽  
Milk Proteins ◽  
Cow’S Milk Allergy ◽  
Food Allergies ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Cow's Milk ◽  
Cow's Milk Allergy ◽  
Cow’S Milk Proteins

Food allergy is an aberrant immune-mediated reaction against harmless food substances, such as cow’s milk proteins. Due to its very early introduction, cow’s milk allergy is one of the earliest and most common food allergies. For this reason cow’s milk allergy can be recognized as one of the first indications of an aberrant inflammatory response in early life. Classically, cow’s milk allergy, as is true for most other allergies as well, is primarily associated with abnormal humoral immune responses, that is, elevation of specific immunoglobulin E levels. There is growing evidence indicating that cellular components of both innate and adaptive immunity play significant roles during the pathogenesis of cow’s milk allergy. This is true for the initiation of the allergic phenotype (stimulation and skewing towards sensitization), development and outgrowth of the allergic disease. This review discusses findings pertaining to roles of cellular immunity in allergic inflammation, and tolerance induction against cow’s milk proteins. In addition, a possible interaction between immune mechanisms underlying cow’s milk allergy and other types of inflammation (infections and noncommunicable diseases) is discussed.

Feeding a soy formula to children with cow's milk allergy: The development of immunoglobulin E-mediated allergy to soy and peanuts

2005 ◽  
Vol 16 (8) ◽  
pp. 641-646 ◽  
Author(s):  
Timo Klemola ◽  
Kirsti Kalimo ◽  
Tuija Poussa ◽  
Kaisu Juntunen-Backman ◽  
Riitta Korpela ◽  
...  
Keyword(s):  
Immunoglobulin E ◽  
Cow’S Milk Allergy ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Cow's Milk ◽  
Cow's Milk Allergy

Immunoglobulin E and Immunoglobulin G4 Antibodies to Cow's Milk in Children with Cow's Milk Allergy

Allergy ◽  
1983 ◽  
Vol 38 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Bengt Björkstéan ◽  
Staffan Ahlstedt ◽  
Fred Björkstéan ◽  
Barbro Carlsson ◽  
Sven Petter Fällström ◽  
...  
Keyword(s):  
Immunoglobulin E ◽  
Cow’S Milk Allergy ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Immunoglobulin G4 ◽  
Cow's Milk ◽  
Cow's Milk Allergy

Allergy

PEDIATRICS ◽  
1991 ◽  
Vol 87 (6) ◽  
pp. 985-992
Keyword(s):  
Solid Phase ◽  
Milk Proteins ◽  
Subsequent Development ◽  
Specific Ige ◽  
Cow’S Milk Allergy ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Cow's Milk ◽  
Cow's Milk Allergy ◽  
Β Lactoglobulin

Pathophysiology MATERNAL IMMUNE STATUS AGAINST β-LACTOGLOBULIN AND COW'S MILK ALLERGY IN THE INFANT Casmir GJA, Duchateau J, Cuvelier P, Vis HL. Ann Allergy. 1989;63:517-519 Purpose of the Study The reported frequency of cow's milk allergy in children varies between 0.3% and 7.5% (population with earlier weaning has higher incidence). A thorough family history of atopy and cord IgE level at birth have been used to predict infants "at risk." Previous studies have shown that high cord IgE level (exceeding 1 IU/mL) was predictive of subsequent development of atopic disease. The purpose of this study was to follow-up the predictive relationship of maternal IgG-anti-BLG (IgG against β-lactoglobulin which is a major cow's milk antigen) and allergic manifestations in the infant. Study Population: Subject Section Mothers. All women were selected from the obstetric department of St Pierre Hospital in Brussels, Belgium. Infants. 69 infants were chosen who were born to these mothers by vaginal delivery and were fed cow's milk. Methods Clinical Evaluation. Every month during the first 6 months of life, infants were examined clinically for allergic symptoms. Gastrointestinal signs (diarrhea, vomiting, colic), atopic dermatitis, and respiratory problems (asthma, chronic cough, rhinitis) were recorded. Symptomatic children were treated with Alfare (Nestle) containing hydrolysates of cow's milk proteins with minimal allergenicity. Biologic Investigations. IgG-anti-BLG levels in mothers' sera were measured using solid-phase radioimmunoassay method. These levels were expressed in arbitrary units per milliliter. All children were screened for total IgE levels at 5 days of age. Specific IgE anti-cow's milk radioallergosorbent tests (RASTs) were performed in all patients at 1 month of age.

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