Does a history of depression influence neuropsychological functioning among older adults?

2014 ◽  
Author(s):  
Elise N. Albert ◽  
Steven A. Rogers
Keyword(s):  
Older Adults ◽  
Neuropsychological Functioning ◽  
History Of ◽  
History Of Depression

scholarly journals 534 - Grief in de elderly and its impact

2021 ◽  
Vol 33 (S1) ◽  
pp. 78-79
Author(s):  
I. Caldas
Keyword(s):  
Older Adults ◽  
The Elderly ◽  
Short Term ◽  
Prolonged Grief ◽  
Loved One ◽  
Death Time ◽  
Pubmed Database ◽  
History Of ◽  
Natural Response ◽  
History Of Depression

IntroductionWith coronavirus disease 2019 (COVID-19) a lot of people have succumbed and older adults were disproportionately affected. (1,2) Also, grief is encountered frequently in clinical practice with the elderly, and can be defined as the natural response to the death of a loved one. Still, when a failure of adaptation occurs then a Prolonged Grief Disorder (PGD) can be diagnosed, which has been recently included in ICD-11. The principal feature of PGD is a persistent preoccupation or an intense longing for the deceased that lasts longer than 6 months after the death. (3)Objective:Comprehend the grief in the elderly and its implications in their health.Methods:The author conducted a literature review by searching the Pubmed database using the keywords elderly; grief; complicated grief; covid-19Results:PGD is relatively prevalent among the elderly and has been associated with some variables related to the death time of the deceased, being the prevalence inversely correlated with the deceased’s. (4, 5) Additionally, older adults present a higher risk of developing PGD when they are lesseducated, male, have poorer cognitive performance, and a history of depression. (3) PGD is characterized by sadness, fascination with or excessive avoidance of the memories associated with the deceased, the memory of the loss and mental ruminations about death. According to some investigations, PGD reduces life expectancy, increasing the odds of death, causes severe behavioural symptoms, and is associated with longer-term functional impairment. (4,5)Conclusion:Given these results, it is easy to understand the need for a closer monitoring of these patients during this global crisis. Moreover, it is also important to find new ways to do that while complying with COVID-19 rules and restrictions. A short-term evidence-based intervention for PGD effective in the elderly is based on support focused upon these seven themes: understanding their grief, managing emotional pain, thinkingabout the future, strengthening their relationships, telling the story of the dead, learning to live with reminders of the deceased, and connecting with memories. (3)

Association between Sleep Disturbances and Medial Temporal Lobe Volume in Older Adults with Mild Cognitive Impairment Free of Lifetime History of Depression

2019 ◽  
Vol 69 (2) ◽  
pp. 413-421 ◽  
Author(s):  
Kimberley Yuen ◽  
Neda Rashidi-Ranjbar ◽  
Nicolaas Paul L.G. Verhoeff ◽  
Sanjeev Kumar ◽  
Damien Gallagher ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Sleep Disturbances ◽  
Lifetime History ◽  
History Of ◽  
History Of Depression

Gray matter characteristics associated with trait anxiety in older adults are moderated by depression

2015 ◽  
Vol 27 (11) ◽  
pp. 1813-1824 ◽  
Author(s):  
Olivier Potvin ◽  
Gwénaëlle Catheline ◽  
Charlotte Bernard ◽  
Céline Meillon ◽  
Valérie Bergua ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Trait Anxiety ◽  
Cortical Thickness ◽  
Gray Matter ◽  
Previous History ◽  
Temporal Cortex ◽  
Anterior Cingulate ◽  
History Of ◽  
History Of Depression

ABSTRACTBackground:Structural gray matter characteristics of anxiety remain unclear. The aim of this study was to assess the influence of current depressive symptoms and history of depression on the gray matter characteristics of trait anxiety.Methods:Structural magnetic resonance imaging (MRI) data from 393 individuals aged 65 years or older were used. Regions of interest (ROIs) included the amygdala, anterior cingulate cortex (ACC), insula, orbitofrontal cortex (OFC), and temporal cortex. Trait anxiety was measured by the State-Trait Anxiety Inventory (STAI). Depression and depressive symptoms were measured using DSM-IV criteria and the Center for Epidemiological Studies Depression Scale (CESD).Results:After adjustments for sociodemographics and health-related variables, anxiety had a significant influence on the gray matter characteristics in all cortical ROIs. First, in participants without depression antecedents, higher trait anxiety was associated with a larger cortical thickness in all cortical ROIs. Second, in participants with a previous history of depression, higher trait anxiety was associated with a smaller cortical thickness in all cortical ROIs.Conclusions:These results suggest that anxiety is related to cortical thickness differently in healthy older adults and in older adults with psychiatric antecedents. Anxiety associated with thinner cortical areas could reflect symptoms of a specific type of depression or a vulnerability to develop depression.

Impairments in Health Functioning and Sleep Quality in Older Adults with a History of Depression

2006 ◽  
Vol 54 (8) ◽  
pp. 1184-1191 ◽  
Author(s):  
Sarosh J. Motivala ◽  
Myron J. Levin ◽  
Michael N. Oxman ◽  
Michael R. Irwin
Keyword(s):  
Older Adults ◽  
Sleep Quality ◽  
Health Functioning ◽  
History Of ◽  
History Of Depression

#3041 High prevalence of lifetime depressive symptoms in patients referred for clinical amyloid-PET: a retrospective study

2021 ◽  
Vol 92 (8) ◽  
pp. A9.1-A9
Author(s):  
Anna Fitzgerald ◽  
Flavia Loreto ◽  
Mara Golemme ◽  
Zarni Win ◽  
Neva Patel ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
Amyloid Pet ◽  
Onset Age ◽  
Appropriate Use Criteria ◽  
Memory Clinic ◽  
Appropriate Use ◽  
History Of ◽  
History Of Depression

Objectives/AimsDepression has been reported as a possible risk factor for Alzheimer’s Disease, but also as one of the clinical features of Alzheimer’s as well as other dementias. Further, depression has long been associated with cognitive impairment in the absence of neurodegeneration (Connors et al. 2018). Here we sought to ascertain the prevalence of clinical depression in patients meeting widely accepted Appropriate Use Criteria for Amyloid PET Imaging (API). We examined the prevalence of lifetime depression in patients undergoing clinical API in a real-world clinical setting and compared our findings with population data from community-dwelling older adults. We also examined whether rates of depression were higher in amyloid positive or negative groups.MethodsOne-hundred-and-eighty-five older adults (mean age 67.079.37, 49% females) underwent diagnostic workup, including API, at the Imperial Memory Clinic between January 2017 and June 2019. API was performed in line with appropriate use criteria after multidisciplinary team discussion. History of depressive symptoms and features of depression were evaluated through a review of hospital records and clinical correspondence. Patients were defined as having a history of depression if there was evidence of previous or current depressive symptoms and/or of a formal diagnosis of depression in their clinical records.ResultsBased on visual reads, 83 individuals had positive Amyloid-PET scans and 102 were negative. Overall, 102 (55%) patients(mean age=66.758.99, 56% females) had a history of lifetime depressive symptoms, compared with just 12 and 19% of elderly individuals in the general population (McDougall et al. 2007; Biddulph et al. 2014). Of the 92 patients for whom further information regarding depression onset were available, 54 (58.7%) had early symptom onset (age <60), and 38 (41.3%) had late symptom onset (age ≥s60). At the time of the clinical assessment at the Imperial Memory Clinic, 71 of those 102 (69.6%) were on active treatment for depression. Finally, depression was not associated with amyloid status (χ2(1) =1.12p=.26), with 42 (41.2%) amyloid-positive and 60 (58.8%) amyloid-negative patients reporting a history of depression.ConclusionsOver half of patients with suspected cognitive impairment and meeting appropriate use criteria for clinical API had a history of depression, regardless of amyloid status. Depression is an important but incompletely understood factor in referral for evaluation with Amyloid-PET.

Sign in / Sign up

Export Citation Format

Share Document