Slow potential change in human brain related to level of motivation.

1967 ◽  
Vol 63 (1) ◽  
pp. 20-23 ◽  
Author(s):  
Charles S. Rebert ◽  
Dale W. McAdam ◽  
John R. Knott
1957 ◽  
Vol 189 (1) ◽  
pp. 159-166 ◽  
Author(s):  
A. Van Harreveld ◽  
Sidney Ochs

Spreading depression is accompanied by a slow potential change, a drop in cortical conductivity and by vascular changes. The latter were investigated in histological preparations of cortex frozen while a spreading depression was in progress. In the cat and rabbit a broad wave of vasodilatation was observed. In the rabbit this appeared to be preceded by a narrow region of vasoconstriction. Spreading depression can be changed into spreading convulsive activity by administering CO2 in the respiratory air (7–12%). CO2 markedly decreased the drop in cortical conductivity but affected the magnitude of the slow potential change only moderately. It is postulated that both the conductivity drop during spreading depression and a similar drop observed after asphyxiation of the brain are caused by a transport of ions from the intercellular compartment into cortical cellular elements. The relationship between the slow potential change, conductivity drop, vascular changes and the changes in the electrocorticogram during spreading depression is discussed.


1937 ◽  
Vol 83 (343) ◽  
pp. 137-155 ◽  
Author(s):  
F. Golla ◽  
S. Graham ◽  
W. Grey Walter

In 1929 Berger (1) discovered that changes of electrical potential in the human brain could be detected through the unopened skull. Since that time the study of electro-encephalography has occupied the attention of many workers, and the literature is already too extensive for adequate review in this place. A brief description of the technique for obtaining an electro-encephalogram, or “EEG”, and a summary of its normal and pathological characters may be found in a communication by one of us (2) on the relation between the EEG and the presence of intracranial neoplasms. The cortex in the region of a tumour was found to produce abnormally slow potential waves, which were provisionally called “delta” (δ) waves to distinguish them from the normal “alpha” (α) waves which are the original “Berger rhythm”. In the same paper a case was reported in which a focus of δ waves was found in the left parieto-occipital region associated with an area of degenerating cortex. The history in this case was of occasional minor attacks and one major fit and an indefinite severe illness in infancy, the only sign being a right homonymous hemianopia in accordance with the left-sided focus. Ether and nitrous oxide anæsthesia are also accompanied by the production of slow waves, but in this condition there is no fixed focus, the whole cortex being engaged in abnormal electrical activity. Since the publication of the above-mentioned results, a case of cerebral abscess has been examined, and the EEG was found to indicate a δ focus similar in character to those which have been found in cases of new growth.


Science ◽  
1958 ◽  
Vol 127 (3303) ◽  
pp. 873-874 ◽  
Author(s):  
A. M. SCHER ◽  
J. LIIKANE ◽  
M. I. RODRIGUEZ ◽  
A. C. YOUNG

1955 ◽  
Vol 184 (1) ◽  
pp. 233-238 ◽  
Author(s):  
A. Van Harreveld ◽  
G. Terres ◽  
E. A. Dernburg

The transmissibility of spreading depression across a cut severing all layers of the cortex was investigated in preparations in which 3 weeks to 3 months was allowed for healing of such an injury. No unequivocal signs of transmission of the spreading depression across the scar were observed, although in some instances the scar was less than 0.1 mm wide. In some experiments a small slow potential change was led off from the cortex on the nonstimulated side by an electrode placed in the immediate vicinity of the scar. This potential was considered as evidence for the physical spread across the scar of the potential field produced by the slow potential change which accompanies the spreading depression on the stimulated side. The failure of transmission of spreading depression across a scar does not support the concept that the slow potential change is the agent involved in the propagation of this phenomenon.


Nature ◽  
1973 ◽  
Vol 242 (5398) ◽  
pp. 465-467 ◽  
Author(s):  
W. C. MCCALLUM ◽  
D. PAPAKOSTOPOULOS ◽  
R. GOMBI ◽  
A. L. WINTER ◽  
R. COOPER ◽  
...  

2005 ◽  
Vol 22 (Supplement 36) ◽  
pp. 20-21
Author(s):  
R. Bhatia ◽  
M. Fabricius ◽  
P. Hashemi ◽  
S. Fuhr ◽  
M. G. Boutelle ◽  
...  

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