Detecting Redox Potentials Using Porous Boron Nitride/ATP-DNA Aptamer/Methylene Blue Biosensor to Monitor Microbial Activities

Microbial activity has gained attention because of its impact on the environment and the quality of people’s lives. Most of today’s methods, which include genome sequencing and electrochemistry, are costly and difficult to manage. Our group proposed a method using the redox potential change to detect microbial activity, which is rooted in the concept that metabolic activity can change the redox potential of a microbial community. The redox potential change was captured by a biosensor consisting of porous boron nitride, ATP-DNA aptamer, and methylene blue as the fluorophore. This assembly can switch on or off when there is a redox potential change, and this change leads to a fluorescence change that can be examined using a multipurpose microplate reader. The results show that this biosensor can detect microbial community changes when its composition is changed or toxic metals are ingested.

Distance Traveled in Times of Pandemic: An Endogenous Switching Regression Approach

This paper studies the change in the distance traveled by domestic tourists considering the pre- and post-pandemic outbreak summer periods of 2019 and 2020. Using representative monthly microdata involving more than 31,000 trips conducted by Spanish residents, we examine the heterogeneity in behavioral adaptation to COVID-19 based on sociodemographic and trip-related characteristics. To account for selection effects and the potential change in the population composition of travelers between the two periods, we estimate an endogenous switching regression that conducts separate regressions for the pre- and post-pandemic periods in a unified econometric framework. Our results point to heterogeneous shifts in the distance traveled by domestic travelers after COVID-19 outbreak per sociodemographic group, with notable differences by travel purpose and lower relevance of traditional determinants like income.

The Dream of the Dragon: A content analysis of Xi Jinping’s “China Dream”

<p>China under Xi Jinping has a story to tell. In recent years, China has devoted more time and energy extending its discursive influence overseas. Aspirational propaganda slogans such as Xi’s “Chinese dream” indicate a potential change from Deng Xiaoping’s “bide your time, hide your strength” towards an outwardly focussed foreign policy of Striving for Achievement as China’s confidence grows. This project conducts a content analysis following the method set out by Klaus Krippendorff of 1907 Xinhua articles from 2013 – 2017 and finds that while this assertion was true shortly after articulation; coverage reverted to an inward focus in subsequent years. Furthermore, the findings show that there is an individualistic aspect to how the dream is portrayed whether it is intended by top government figures or not. Understanding how tifa develop, interrelate – or depart from each other – is vital in understanding contemporary political discourse in China. Lastly, the Chinese dream contains within it the beginnings of a prototype vision of Chinese exceptionalism.</p>

The Dream of the Dragon: A content analysis of Xi Jinping’s “China Dream”

<p>China under Xi Jinping has a story to tell. In recent years, China has devoted more time and energy extending its discursive influence overseas. Aspirational propaganda slogans such as Xi’s “Chinese dream” indicate a potential change from Deng Xiaoping’s “bide your time, hide your strength” towards an outwardly focussed foreign policy of Striving for Achievement as China’s confidence grows. This project conducts a content analysis following the method set out by Klaus Krippendorff of 1907 Xinhua articles from 2013 – 2017 and finds that while this assertion was true shortly after articulation; coverage reverted to an inward focus in subsequent years. Furthermore, the findings show that there is an individualistic aspect to how the dream is portrayed whether it is intended by top government figures or not. Understanding how tifa develop, interrelate – or depart from each other – is vital in understanding contemporary political discourse in China. Lastly, the Chinese dream contains within it the beginnings of a prototype vision of Chinese exceptionalism.</p>

Exploring the transformative potential of urban food

Urban food is a key lever for transformative change towards sustainability. While research reporting on the urban food practices (UFPs) in support of sustainability is increasing, the link towards transformative potential is lacking. This is because research on urban food is often place-based and contextual. This limits the applicability of insights to large-scale sustainability transformations. This paper describes UFPs that aim to contribute to transformative change. We present signposts for potential change based on the types of intended transformative changes as described in the reviewed literature based on the processes and outcomes of the urban food policies and programmes. Secondly, we classify diverse UFPs to elevate them beyond their local, place-based contexts. We find that UFPs carry a lot of potential to facilitate sustainability transformations. Based on that analysis, we provide insights on how urban food research can further contribute to harnessing the transformative potential of UFPs for actionable purposes.

Unfinished Reform of the Institutions Enforcing UK Competition Law

Chapter 8 on institutional reform written by Bruce Lyons notes that the period since 1998 has seen major changes in competition law, including: public interest was replaced by promotion of competition as the primary duty; anti-competitive agreements and abuse of a dominant position were prohibited, with significant penalties for breach; and the minister withdrew from case decisions, making the institutions determinative. There were also major organizational changes, including merger of the OFT and the Competition Commission to form the Competition and Markets Authority, and establishment of the Competition Appeal Tribunal as a specialist appeals body. In the chapter, Lyons considers the evolution of these institutions from the perspective of how they frame and influence the quality of first instance determinations. Institutions are hostages to their history, and he traces some of the problems faced by the CMA to its institutional roots. New challenges beyond its control are also identified. Reform is needed. The chapter concludes that some of the CMA’s suggestions for legislation are misguided, particularly in replacing its competition duty with ‘the consumer interest’ and reducing the standard of review by the CAT. Alternative proposals are appraised, including a potential change to a prosecutorial system. Lyons argues convincingly that genuinely independent decision-making within the CMA should be preferred and would permit a more limited standard of review.

Information-theoretic View of the Variation of the Gravitational Constant

Many recent theories speak of the spatial and temporal variations of the fundamental “constants”, and experiments have been performed to determine the variation. It has also been proposed that the variation of these constants is related to the strength of the gravitational potential whose changes, therefore, assume special significance. Here we examine potential change in G from the information-theoretic perspective of noninteger dimensionality and determine a relationship with respect to time. We show that the rate of change using this method is of the same order as estimated using other approaches.

Information-theoretic View of the Variation of the Gravitational Constant

Many recent theories speak of the spatial and temporal variations of the fundamental “constants”, and experiments have been performed to determine the variation. It has also been proposed that the variation of these constants is related to the strength of the gravitational potential whose changes, therefore, assume special significance. Here we examine potential change in G from the information-theoretic perspective of noninteger dimensionality and determine a relationship with respect to time. We show that the rate of change using this method is of the same order as estimated using other approaches.

Potentiometric Response of Solid-State Sensors Based on Ferric Phosphate for Iron(III) Determination

A novel ion-selective electrode with membranes based on iron(III) phosphate and silver sulfide integrated into a completely new electrode body design has been developed for the determination of iron(III) cations. The best response characteristics with linear potential change were found in the iron(III) concentration range from 3.97× 10−5 to 10−2 mol L−1. The detection limit was found to be 2.41× 10−5 mol L−1 with a slope of –20.53 ± 0.63 and regression coefficient of 0.9925, while the quantification limit was 3.97× 10−5 M. The potential change per concentration decade ranged from –13.59 ± 0.54 to –20.53 ± 1.56 for Electrode Body 1 (EB1) and from –17.28 ± 1.04 to –24 ± 1.87 for Electrode Body 2 (EB2), which is presented for the first time in this work. The prepared electrode has a long lifetime and the ability to detect changes in the concentration of iron cations within 20 s. Membrane M1 showed high recoveries in the determination of iron cations in iron(III) standard solutions (98.2–101.2%) as well as in two different pharmaceuticals (98.6–106.5%). This proves that this type of sensor is applicable in the determination of ferric cations in unknown samples, and the fact that all sensor parts are completely manufactured in our laboratory proves the simplicity of the method.

How Does Adding the DSM-5 Criterion Increased Energy/Activity for Mania Change the Bipolar Landscape?

According to DSM-IV, the criterion (A) for diagnosing hypomanic/manic episodes is mood change (i.e., elevated, expansive or irritable mood). Criterion (A) was redefined in DSM-5 in 2013, adding increased energy/activity in addition to mood change. This paper examines a potential change of prevalence data for bipolar I or II when adding increased energy/activity to the criterion (A) for the diagnosis of hypomania/mania. Own research suggests that the prevalence of manic/hypomanic episodes drops by at least one third when using DSM-5 criteria. Whether this has positive or negative impact on clinical practice and research still needs further evaluation.