Pregnant Mare Serum Gonadotrophin Potency: Effect of Single and Multiple Injections

Nature ◽  
1965 ◽  
Vol 207 (4995) ◽  
pp. 412-413 ◽  
Author(s):  
GERALD M. CONNELL
2010 ◽  
Vol 70 (22) ◽  
pp. 9053-9061 ◽  
Author(s):  
Yangbing Zhao ◽  
Edmund Moon ◽  
Carmine Carpenito ◽  
Chrystal M. Paulos ◽  
Xiaojun Liu ◽  
...  

1995 ◽  
Vol 32 (1-4) ◽  
pp. 275-279 ◽  
Author(s):  
Catharina Brandsten ◽  
Idil Alatli ◽  
Tilmann Wurtz ◽  
Lars Hammarström

1986 ◽  
Vol 110 (3) ◽  
pp. 507-510 ◽  
Author(s):  
T. Sawada

ABSTRACT Differences in the secretion of pregnane compounds by follicular polycystic ovaries of androgen-sterilized rats and by normal preovulatory ovaries of early prooestrous rats were compared. Some rats were injected i.v. with LH 30 min before bleeding, in order to stimulate the secretion of steroids. This injection of LH greatly increased the secretion of progesterone, 5α-pregnane-3,20-dione and 3α-hydroxy-5α-pregnan-20-one by both types of ovaries. The response of the two progesterone metabolites in the polycystic ovaries was low, suggesting low 5α-reductase activity. Because it is known that the preovulatory LH surge is absent in androgen-sterilized rats, a classical approach was taken to circumvent the probable deficit in cyclic release of LH by giving an i.v. injection of LH (25 μg) every 4 days for 16 days. Ovarian venous blood was collected 4 days after the last injection. The mean secretion of 5α-pregnane-3,20-dione and 3α-hydroxy-5α-pregnan-20-one from the ovaries of such androgen-sterilized rats became much (P <0·01) higher than that of multiple saline-treated controls. These results suggest that low 5α-reductase activity of polycystic ovaries in androgen-sterilized rats may be due to the absence of cyclic release of LH from the pituitary gland. J. Endocr. (1986) 110, 507–510


2013 ◽  
pp. 467 ◽  
Author(s):  
Galor ◽  
Hurmeric ◽  
Vaddavalli ◽  
Perez ◽  
San Roman ◽  
...  

2020 ◽  
Vol 12 (12) ◽  
pp. 168781402098462
Author(s):  
Yingying Lu ◽  
Yize Liu

Advanced multiple injection strategies have been suggested for compression ignition engines in order to meet the increasingly stringent emission regulations. Experiments and simulations were used to study effects of the main-injection mode (times), the post-injection proportion, and timing on combustion and emissions in a heavy-duty diesel engine at high load and constant low speed. The results reveal the following. The NOx emissions of 1main+1post, 2main+1post, and 3main+1post injections are all lower than those of single injection; the higher the number of main-injection pluses, the lower the NOx emissions. Enough main-post injection interval is needed to ensure post and main injections are relatively independent to entrain more fresh air to decrease the soot. Over-retarded post-injection timing tends to increase the soot due to the lower in-cylinder temperature. The combined effects of formation and oxidation determine the final soot. To gain the best trade-off of NOx and soot, compared with single injection, for the three multiple injections, the lowest soot emissions are gained at post-injection proportions of 15% and post-injection timings of 25°, 30°, and 35° CA ATDC, with soot reductions of 26.7%, −34.5%, and −112.8%, and NOx reductions of 5.88%, 21.2%, and 40.3%, respectively, for 1main+1post, 2main+1post, and 3main+1post injections.


Reproduction ◽  
1975 ◽  
Vol 44 (1) ◽  
pp. 95-100 ◽  
Author(s):  
J. E. A. McINTOSH ◽  
R. M. MOOR ◽  
W. R. ALLEN

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