Triiodothyronine, diluted according homeopathic techniques, modifies the programmed cell death of tadpole tail's explants

High Dilution is a solution beyond the Avogadro limits that, in the dependence of the applied succussion elicits a suppressive or a stimulant effect on a living cell, with a consequent generation of an oscillatory dose-effect curve. According to Bonamin et al. [1], “Perhaps, the most enigmatic feature regarding the properties of high dilutions is the non-linearity of their effects. In several studies employing in vivo and ex vivo models, especially involving iso-endopathy, an oscillatory potency-effect curve has appeared. The first observations were initially considered as artifacts, but the repetition of this pattern in different studies involving completely different experimental models, in times and places equally different, points out to the existence of a property intrinsic to dynamized systems.” ...

Characterization of an umbilical cord blood sourced product suitable for allogeneic applications

Aim: Umbilical cord blood (UCB) sourced allografts are promising interventions for tissue regeneration. As applications of these allografts and regulations governing them continue to evolve, we were prompted to identify parameters determining their quality, safety and regenerative potential. Materials & methods: Flow-cytometry, mass-spectrometry, protein multiplexing, nanoparticle tracking analysis and standard biological techniques were employed. Results: Quality attributes of a uniquely processed UCB-allograft (UCBr) were enumerated based on identity (cell viability, immunophenotyping, proteomic profiling, and quantification of relevant cytokines); safety (bioburden and microbiological screening), purity (endotoxin levels) and potency (effect of UCBr on chondrocytes and mesenchymal stem cells derived exosomes). These attributes were stable up to 24 months in cryopreserved UCBr. Conclusion: We identified a comprehensive panel of tests to establish the clinical efficacy and quality control attributes of a UCB-sourced allograft.

Content and Order in the Formation of Impressions

Two contrasting character descriptions from each of three short stories were rated by Ss on a set of semantic differential scales and a set of descriptive statements. Ratings were obtained for two orders of presentation and in two conditions of judgment. In one condition, a rating was introduced after the reading of the first story section, as well as at the conclusion of reading the second section. In the other condition, the rating occurred only at the conclusion of reading the second section. The results indicate that some story sections dominate the final judgment regardless of order or interpolated judgment. When such a potency effect is not a factor, primacy (first impression) effects occur when intermediate judgment is not interpolated, and recency (last impression) effects are strengthened when intermediate judgment is interpolated. For two of the three characters the potency of one episode influenced final impressions. The design of the study permits an analysis of content effects in impression-formation and the results suggest the value of the further investigation of content variables which influence the judgment of characteristics of others.