Increased hyaluronic acid production on stimulation of DNA synthesis in chick embryo fibroblasts

Nature ◽  
1975 ◽  
Vol 254 (5495) ◽  
pp. 65-66 ◽  
Author(s):  
DAVID MOSCATELLI ◽  
HARRY RUBIN
Keyword(s):  
Hyaluronic Acid ◽  
Chick Embryo ◽  
Dna Synthesis ◽  
Acid Production ◽  
Embryo Fibroblasts ◽  
Hyaluronic Acid Production ◽  
Stimulation Of

Growth Hormone-Dependent Serum Stimulation of DNA Synthesis in Chick Embryo Fibroblasts in Culture12

Endocrinology ◽  
1975 ◽  
Vol 96 (1) ◽  
pp. 193-198 ◽  
Author(s):  
KENNETH L. COHEN ◽  
PATRICIA A. SHORT ◽  
S. PETER NISSLEY
Keyword(s):  
Growth Hormone ◽  
Chick Embryo ◽  
Dna Synthesis ◽  
Serum Stimulation ◽  
Embryo Fibroblasts ◽  
Stimulation Of

The effect of exogenous RNA extract on chick embryo fibroblasts in vitro

Development ◽  
1970 ◽  
Vol 23 (2) ◽  
pp. 509-517
Author(s):  
A. Sann ◽  
D. Sharp ◽  
J. McKenzie
Keyword(s):  
Cell Differentiation ◽  
Chick Embryo ◽  
Morphological Changes ◽  
Bacterial Cells ◽  
Baby Hamster Kidney ◽  
Exogenous Rna ◽  
Embryo Fibroblasts ◽  
Stimulation Of ◽  
Rna Extract

It is extremely difficult, if not impossible, to reconcile the conflicting claims of those who have treated different cells and tissues with exogenous RNA. Some authors (e.g. Niu, Cordova & Niu, 1961; Niu, Cordova & Radbill, 1962) maintain that RNA extracts alter the course of cell differentiation to conform in morphological terms to the source of the RNA; in the same vein, Amos, Askonas & Soeiro (1964) have shown that, under certain conditions, RNA from mouse and bacterial cells can stimulate chick embryo fibroblasts to synthesize protein related antigenically to the origin of the RNA. Shepley, Ambrose & Kirby (1965), however, obtained stimulation of growth with permanent morphological changes in baby hamster kidney fibroblasts by the addition of RNA from a variety of sources.

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