β-Endorphin and dynorphin control serum luteinizing hormone level in immature female rats

Nature ◽  
1981 ◽  
Vol 294 (5843) ◽  
pp. 757-759 ◽  
Author(s):  
Rüdiger Schulz ◽  
Annemarie Wilhelm ◽  
Karl Martin Pirke ◽  
Christian Gramsch ◽  
Albert Herz
1991 ◽  
Vol 5 (4) ◽  
pp. 223-233 ◽  
Author(s):  
J. Urbancsek ◽  
T. Rabe ◽  
K. Grunwald ◽  
L. Kiesel ◽  
Z. Pappt ◽  
...  

1975 ◽  
Vol 66 (1) ◽  
pp. 13-20 ◽  
Author(s):  
D. C. JOHNSON ◽  
R. S. MALLAMPATI

SUMMARY Release of immunoreactive LH and FSH was induced in immature intact female rats by repeated injections of synthetic luteinizing hormone releasing hormone (LH-RH). Altering the dose of LH-RH (5, 10, 20, 50 ng) and the frequency of administration (every 10, 20, 30 or 60 min) over a period of 2 h produced a variety of serum LH and FSH concentrations and ratios. When the dose was a constant 20 ng but the frequency of injections was either 20 or 30 min, a steady state in serum gonadotrophin concentrations was reached within 1 h and the level remained the same during the second hour. When given every 10 min, 20 ng LH-RH produced a much higher concentration of both LH and FSH during the second hour of stimulation. Examination of the gonadotrophin levels after each injection of LH-RH showed that the pituitary response was variable in spite of a constant stimulus.


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