scholarly journals Maternal ABO blood group and adverse pregnancy outcomes

2012 ◽  
Vol 33 (2) ◽  
pp. 107-111 ◽  
Author(s):  
C Phaloprakarn ◽  
S Tangjitgamol
Keyword(s):  
Blood Group ◽  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Abo Blood Group ◽  
Adverse Pregnancy

scholarly journals Effect of maternal ABO blood type on birth weight and preeclampsia

2017 ◽  
Vol 6 (6) ◽  
pp. 2164 ◽  
Author(s):  
Fatma Beyazıt ◽  
Eren Pek ◽  
Aysenur Çakır Güngör ◽  
Meryem Gencer ◽  
Mesut A. Unsal
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Blood Group ◽  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Blood Type ◽  
Abo Blood Group ◽  
Abo Blood Groups ◽  
Type B ◽  
Adverse Pregnancy

Background: ABO blood group has been recognized as a risk factor for distinct disease states. The association between ABO blood group and adverse pregnancy outcomes has not been extensively studied, especially in relation to birth weight and preeclampsia (PE). The aim of the present study is to determine whether ABO blood group contributes to the adverse pregnancy outcomes including low birth weight and PE.Methods: Medical data including ABO phenotypes were collected from hospital electronic database and retrospectively reviewed. Adverse pregnancy outcomes included PE and low birth weight. Birth week was also noted for each subject.Results: 2177 charts of mothers who had given birth in our hospital were studied. Overall 605 (27.8%) women had type O blood, 1056 (48.5%) had type A blood, 369 (16.9%) had type B blood and 147 (6.8%) had type AB blood. Pregnant women with type B blood group had significantly lower birth weights compared with type O, A and AB. Birth weeks of all groups were found to be similar with no statistically significant difference. A total of 167 mothers were recorded as having PE. No association was observed between PE and ABO blood groups of study participants.Conclusions: Although maternal ABO phenotype is associated with low birth weight, no association was found between blood type and preeclampsia. We postulate that maternal/fetal immune system genes which are directly associated with ABO blood groups could affect pregnant with a resulting birth weight alterations.

scholarly journals EFFECT OF MATERNAL ABO BLOOD TYPE ON BIRTH WEIGHT

2021 ◽  
pp. 183-186
Author(s):  
Dr.Himanshu S Dave ◽  
Dr.Tanushree Joshi ◽  
Dr.Kathakali Das ◽  
Dr.Dimple Pal
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Blood Group ◽  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Blood Type ◽  
Abo Blood Group ◽  
Type B ◽  
Abo Blood Type ◽  
Adverse Pregnancy

Background: ABO blood group has been recognized as a risk factor for distinct disease states. The association between ABO blood group and adverse pregnancy outcomes has not been extensively studied, especially in relation to birth weight. The aim of the present study is to determine whether ABO blood group contributes to the adverse pregnancy outcomes like low birth weight. Methods: Medical data including ABO phenotypes were collected from hospital database and retrospectively reviewed. Adverse pregnancy outcome studied was low birth weight. Birth week was also noted for each subject. Results: 500 charts of mothers who had given birth in our hospital were studied. Overall 146 (29.2%) women had type O blood, 108 (21.6%) had type A blood, 194 (38.8%) had type B blood and 52 (10.4%) had type AB blood. Pregnant women with type B blood group had significantly lower birth weights compared with type O, A and AB. Birth weeks of all groups were found to be similar with no statistically significant difference Conclusions: Maternal ABO phenotype is associated with low birth weight, while no association was found between blood type and birth week. We postulate that maternal/fetal immune system genes which are directly associated with ABO blood groups could affect pregnant with a resulting birth weight alterations. KEYWORDS: ABO blood type, Birth weight, Pregnancy.

Association between Thiopurines Use and Pregnancy Outcomes in Female Patients with Inflammatory Bowel Disease: A Meta-analysis

2020 ◽  
Vol 26 ◽  
Author(s):  
Yang Zhang ◽  
Dandan Li ◽  
Heng Guo ◽  
Weina Wang ◽  
Xingang Li ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Preterm Birth ◽  
Spontaneous Abortion ◽  
Bowel Disease ◽  
Pregnancy Outcomes ◽  
Congenital Malformations ◽  
Meta Analysis ◽  
Adverse Pregnancy Outcomes ◽  
Inflammatory Bowel ◽  
Adverse Pregnancy

Background: Conflicting data exist regarding the influence of thiopurines exposure on adverse pregnancy outcomes in female patients with inflammatory bowel disease (IBD). Objective: The aim of this study was to provide an up-to-date and comprehensive assessment of the safety of thiopurines in pregnant IBD women. Methods: All relevant articles reporting pregnancy outcomes in women with IBD received thiopurines during pregnancy were identified from the databases (PubMed, Embase, Cochrane Library, and ClinicalTrials.gov) with the publication data up to April 2020. Data of included studies were extracted to calculate the relative risk (RR) of multiple pregnancy outcomes: congenital malformations, low birth weight (LBW), preterm birth, small for gestational age (SGA), and spontaneous abortion. The meta-analysis was performed using the random-effects model. Results: Eight studies matched with the inclusion criteria and a total of 1201 pregnant IBD women who used thiopurines and 4189 controls comprised of women with IBD received drugs other than thiopurines during pregnancy were included. Statistical analysis results demonstrated that the risk of preterm birth was significantly increased in the thiopurine-exposed group when compared to IBD controls (RR, 1.34; 95% CI, 1.00-1.79; p=0.049; I 2 =41%), while no statistically significant difference was observed in the incidence of other adverse pregnancy outcomes. Conclusion: Thiopurines’ use in women with IBD during pregnancy is not associated with congenital malformations, LBW, SGA, or spontaneous abortion, but appears to have an association with an increased risk of preterm birth.

The Need for Personalized Risk-Stratified Approaches to Treatment for Gestational Diabetes: A Narrative Review

2021 ◽  
Author(s):  
Shamil D. Cooray ◽  
Jacqueline A. Boyle ◽  
Georgia Soldatos ◽  
Shakila Thangaratinam ◽  
Helena J. Teede
Keyword(s):  
Gestational Diabetes ◽  
Pregnancy Outcomes ◽  
Population Based ◽  
Adverse Pregnancy Outcomes ◽  
Therapeutic Interventions ◽  
Clinical Prediction Model ◽  
Increased Risk ◽  
Adverse Pregnancy ◽  
The Individual ◽  
Personalized Risk

AbstractGestational diabetes mellitus (GDM) is common and is associated with an increased risk of adverse pregnancy outcomes. However, the prevailing one-size-fits-all approach that treats all women with GDM as having equivalent risk needs revision, given the clinical heterogeneity of GDM, the limitations of a population-based approach to risk, and the need to move beyond a glucocentric focus to address other intersecting risk factors. To address these challenges, we propose using a clinical prediction model for adverse pregnancy outcomes to guide risk-stratified approaches to treatment tailored to the individual needs of women with GDM. This will allow preventative and therapeutic interventions to be delivered to those who will maximally benefit, sparing expense, and harm for those at a lower risk.

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