Hairpin structures play an essential role in replication, transcription and recombination. Single molecule studies enable real-time measurement and observation of energetics and dynamics of hairpin structures, including folding and DNA-protein...
Nanopipettes were used for real-time investigation into actin dynamics and drug binding at single-molecule resolution, showing promise for a better understanding of the mechanism of protein–protein interactions and drug discovery.
Real-time measurement of protein–protein interactions at single-molecule resolution using a biological nanopore
