Postmitotic control of sensory area specification during neocortical development

The neocortex is an exquisitely organized structure achieved through complex cellular processes from the generation of neural cells to their integration into cortical circuits after complex migration processes. During this long journey, neural cells need to establish and release adhesive interactions through cell surface receptors known as cell adhesion molecules (CAMs). Several types of CAMs have been described regulating different aspects of neurodevelopment. Whereas some of them mediate interactions with the extracellular matrix, others allow contact with additional cells. In this review, we will focus on the role of two important families of cell–cell adhesion molecules (C-CAMs), classical cadherins and nectins, as well as in their effectors, in the control of fundamental processes related with corticogenesis, with special attention in the cooperative actions among the two families of C-CAMs.

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Mechanisms of neocortical development

The Journal of Physiology ◽

10.1113/jphysiol.2009.171470 ◽

2009 ◽

Vol 587 (9) ◽

pp. 1871-1872 ◽

Cited By ~ 1

Author(s):

John T. R. Isaac ◽

Dirk Feldmeyer

Keyword(s):

Neocortical Development

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117 Alpha2A adrenoceptor expression during neocortical development

International Journal of Developmental Neuroscience ◽

10.1016/0736-5748(96)80307-8 ◽

1996 ◽

Vol 14 ◽

pp. 78-78

Author(s):

U.H. Winzer-Serhan ◽

F.M. Leslie

Keyword(s):

Neocortical Development

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VII. The exact histological localisation of the visual area of the human cerebral cortex

Philosophical Transactions of the Royal Society of London Series B Containing Papers of a Biological Character (1896-1934) ◽

10.1098/rstb.1900.0013 ◽

1900 ◽

Vol 193 (185-193) ◽

pp. 165-222 ◽

Cited By ~ 47

Keyword(s):

Cerebral Cortex ◽

County Council ◽

Visual Area ◽

Human Cerebral Cortex ◽

Human Cortex ◽

Physiological Laboratory ◽

Sensory Area ◽

University College ◽

Cortex Cerebri

The object of the present paper is to define by histological methods the exact limitations of the visuo-sensory area of the human cortex cerebri. The investigation to be described has occupied upwards of three years. It was commenced during the summer of 1896 in the pathological laboratory of the County Asylum, Rainhill, Lancashire; it was continued during the next three years in the physiological laboratory of Mason University College, Birmingham; and it has been completed in the pathological laboratory of the London County Council at Claybury. Owing to the remarkable facilities for research granted to workers in the last-named laboratory, it has been possible to bring this investigation to a much more rapid conclusion than would otherwise have been possible. A general summary of the paper follows this introduction, and it is succeeded for convenience of reference by a list of the sections into which the paper is divided.

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