scholarly journals Genome-wide association analyses in east Asians identify new susceptibility loci for colorectal cancer

2012 ◽  
Vol 45 (2) ◽  
pp. 191-196 ◽  
Author(s):  
Wei-Hua Jia ◽  
◽  
Ben Zhang ◽  
Keitaro Matsuo ◽  
Aesun Shin ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Genome Wide Association ◽  
Susceptibility Loci ◽  
East Asians ◽  
Association Analyses ◽  
Genome Wide

scholarly journals Genome-wide association analyses identify two susceptibility loci for pachychoroid disease central serous chorioretinopathy

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Yoshikatsu Hosoda ◽  
Masahiro Miyake ◽  
Rosa L. Schellevis ◽  
Camiel J. F. Boon ◽  
Carel B. Hoyng ◽  
...  
Keyword(s):  
Odds Ratio ◽  
Central Serous Chorioretinopathy ◽  
Genome Wide Association Study ◽  
Risk Allele ◽  
Age Related Macular Degeneration ◽  
Genome Wide Association ◽  
Susceptibility Loci ◽  
Association Analyses ◽  
Age Related ◽  
Genome Wide

AbstractThe recently emerged pachychoroid concept has changed the understanding of age-related macular degeneration (AMD), which is a major cause of blindness; recent studies attributed AMD in part to pachychoroid disease central serous chorioretinopathy (CSC), suggesting the importance of elucidating the CSC pathogenesis. Our large genome-wide association study followed by validation studies in three independent Japanese and European cohorts, consisting of 1546 CSC samples and 13,029 controls, identified two novel CSC susceptibility loci: TNFRSF10A-LOC389641 and near GATA5 (rs13278062, odds ratio = 1.35, P = 1.26 × 10−13; rs6061548, odds ratio = 1.63, P = 5.36 × 10−15). A T allele at TNFRSF10A-LOC389641 rs13278062, a risk allele for CSC, is known to be a risk allele for AMD. This study not only identified new susceptibility genes for CSC, but also improves the understanding of the pathogenesis of AMD.

scholarly journals Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo

2012 ◽  
Vol 44 (6) ◽  
pp. 676-680 ◽  
Author(s):  
Ying Jin ◽  
Stanca A Birlea ◽  
Pamela R Fain ◽  
Tracey M Ferrara ◽  
Songtao Ben ◽  
...  
Keyword(s):  
Genome Wide Association ◽  
Susceptibility Loci ◽  
Association Analyses ◽  
Genome Wide

scholarly journals Genome wide association identified colorectal cancer susceptibility loci and colorectal cancer risk in Lynch syndrome

2010 ◽  
Vol 8 (Suppl 1) ◽  
pp. P16
Author(s):  
Mala Pande ◽  
Marsha L Frazier ◽  
Patrick M Lynch ◽  
Russell Broaddus ◽  
Christopher I Amos
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Lynch Syndrome ◽  
Cancer Susceptibility ◽  
Colorectal Cancer Risk ◽  
Genome Wide Association ◽  
Susceptibility Loci ◽  
Genome Wide

scholarly journals Genome-Wide Association Study in East Asians Identifies Novel Susceptibility Loci for Breast Cancer

PLoS Genetics ◽  
2012 ◽  
Vol 8 (2) ◽  
pp. e1002532 ◽  
Author(s):  
Jirong Long ◽  
Qiuyin Cai ◽  
Hyuna Sung ◽  
Jiajun Shi ◽  
Ben Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Susceptibility Loci ◽  
East Asians ◽  
Genome Wide

scholarly journals Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians

2014 ◽  
Vol 135 (4) ◽  
pp. 948-955 ◽  
Author(s):  
Ben Zhang ◽  
Wei-Hua Jia ◽  
Keitaro Matsuo ◽  
Aesun Shin ◽  
Yong-Bing Xiang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Colorectal Cancer Risk ◽  
Genome Wide Association ◽  
East Asians ◽  
Risk Variant ◽  
Genome Wide

scholarly journals Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer

2016 ◽  
Vol 48 (12) ◽  
pp. 1544-1550 ◽  
Author(s):  
Corina Lesseur ◽  
Brenda Diergaarde ◽  
Andrew F Olshan ◽  
Victor Wünsch-Filho ◽  
Andrew R Ness ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Genome Wide Association ◽  
Susceptibility Loci ◽  
Pharyngeal Cancer ◽  
Association Analyses ◽  
Genome Wide

scholarly journals Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer

2019 ◽  
Vol 156 (5) ◽  
pp. 1455-1466 ◽  
Author(s):  
Yingchang Lu ◽  
Sun-Seog Kweon ◽  
Chizu Tanikawa ◽  
Wei-Hua Jia ◽  
Yong-Bing Xiang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Association Study ◽  
Large Scale ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
East Asians ◽  
Genome Wide

scholarly journals Erratum: Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis

2013 ◽  
Vol 45 (6) ◽  
pp. 714-714
Author(s):  
Min Deng ◽  
Ling Wei ◽  
Xianbo Zuo ◽  
Yanghua Tian ◽  
Fei Xie ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Han Chinese ◽  
Genome Wide Association ◽  
Susceptibility Loci ◽  
Association Analyses ◽  
Genome Wide ◽  
Lateral Sclerosis
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