Integrated Pharmacometrics and Systems Pharmacology Model-Based Analyses to Guide GnRH Receptor Modulator Development for Management of Endometriosis

Faculty Opinions recommendation of Integrated pharmacometrics and systems pharmacology model-based analyses to guide GnRH receptor modulator development for management of endometriosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717975911.793470319 ◽

2013 ◽

Author(s):

Murali Ramanathan ◽

Jonathan Knights

Keyword(s):

Gnrh Receptor ◽

Systems Pharmacology ◽

Model Based ◽

Receptor Modulator ◽

Faculty Opinions recommendation of Use of a Systems Pharmacology Model Based Approach Toward Dose Optimization of Parathyroid Hormone Therapy in Hypoparathyroidism.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734280985.793560241 ◽

2019 ◽

Author(s):

Piet van der Graaf

Keyword(s):

Parathyroid Hormone ◽

Hormone Therapy ◽

Dose Optimization ◽

Systems Pharmacology ◽

Model Based ◽

Quantitative Systems Pharmacology Model-Based Predictions of Clinical Endpoints to Optimize Warfarin and Rivaroxaban Anti-Thrombosis Therapy

Frontiers in Pharmacology ◽

10.3389/fphar.2020.01041 ◽

2020 ◽

Vol 11 ◽

Author(s):

Sonja Hartmann ◽

Konstantinos Biliouris ◽

Lawrence J. Lesko ◽

Ulrike Nowak-Göttl ◽

Mirjam N. Trame

Keyword(s):

Systems Pharmacology ◽

Clinical Endpoints ◽

Model Based ◽

Quantitative systems pharmacology model‐based investigation of Adverse Gastrointestinal Events Associated with Prolonged Treatment with PI3‐Kinase (PI3K) Inhibitors

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12749 ◽

2021 ◽

Author(s):

Kapil Gadkar ◽

Christina Friedrich ◽

Vincent Hurez ◽

Maria‐Luisa Ruiz ◽

Leslie Dickmann ◽

...

Keyword(s):

Pi3 Kinase ◽

Prolonged Treatment ◽

Systems Pharmacology ◽

Pi3k Inhibitors ◽

Model Based ◽

Gastrointestinal Events ◽

Use of a Systems Pharmacology Model Based Approach Toward Dose Optimization of Parathyroid Hormone Therapy in Hypoparathyroidism

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1200 ◽

2018 ◽

Vol 105 (3) ◽

pp. 710-718 ◽

Cited By ~ 5

Author(s):

Manoj Khurana ◽

Immo Zadezensky ◽

Naomi Lowy ◽

Dragos Roman ◽

Jean-Marc Guettier ◽

...

Keyword(s):

Parathyroid Hormone ◽

Hormone Therapy ◽

Dose Optimization ◽

Systems Pharmacology ◽

Model Based ◽

Dynamical systems analysis as an additional tool to inform treatment outcomes: The case study of a quantitative systems pharmacology model of immuno-oncology

Chaos An Interdisciplinary Journal of Nonlinear Science ◽

10.1063/5.0022238 ◽

2021 ◽

Vol 31 (2) ◽

pp. 023124

Author(s):

Aymen Balti ◽

Didier Zugaj ◽

Frédérique Fenneteau ◽

Pierre-Olivier Tremblay ◽

Fahima Nekka

Keyword(s):

Dynamical Systems ◽

Treatment Outcomes ◽

Systems Analysis ◽

Systems Pharmacology ◽

Additional Tool ◽

Dynamical Systems Analysis ◽

Quantitative systems pharmacology model of thrombopoiesis and platelet life‐cycle, and its application to thrombocytopenia based on chronic liver disease

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12623 ◽

2021 ◽

Author(s):

Ryosuke Shimizu ◽

Takayuki Katsube ◽

Toshihiro Wajima

Keyword(s):

Life Cycle ◽

Liver Disease ◽

Chronic Liver Disease ◽

Chronic Liver ◽

Systems Pharmacology ◽

A Systems Pharmacology Model for Drug Delivery to Solid Tumors by Antibody-Drug Conjugates: Implications for Bystander Effects

The AAPS Journal ◽

10.1208/s12248-019-0390-2 ◽

2019 ◽

Vol 22 (1) ◽

Cited By ~ 3

Author(s):

Jackson K. Burton ◽

Dean Bottino ◽

Timothy W. Secomb

Keyword(s):

Drug Delivery ◽

Solid Tumors ◽

Systems Pharmacology ◽

Bystander Effects ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

Antibody Drug ◽

A Quantitative Systems Pharmacology Model of T Cell Engager Applied to Solid Tumor

The AAPS Journal ◽

10.1208/s12248-020-00450-3 ◽

2020 ◽

Vol 22 (4) ◽

Cited By ~ 4

Author(s):

Huilin Ma ◽

Hanwen Wang ◽

Richard J. Sove ◽

Mohammad Jafarnejad ◽

Chia-Hung Tsai ◽

...

Keyword(s):

T Cell ◽

Solid Tumor ◽

Systems Pharmacology ◽

A Quantitative Systems Pharmacology Model for the Key Interleukins Involved in Crohn's Disease

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.119.260539 ◽

2019 ◽

Vol 372 (3) ◽

pp. 299-307

Author(s):

Violeta Balbas-Martinez ◽

Eduardo Asin-Prieto ◽

Zinnia P. Parra-Guillen ◽

Iñaki F. Troconiz

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Systems Pharmacology ◽