Meta-analysis of human prediction error for incentives, perception, cognition, and action

Author(s):  
Philip R. Corlett ◽  
Jessica A. Mollick ◽  
Hedy Kober
2021 ◽  
Author(s):  
Philip R. Corlett ◽  
Jessica A Mollick ◽  
Hedy Kober

Prediction errors (PEs) are a keystone for computational neuroscience. Their association with midbrain neural firing has been confirmed across species and has inspired the construction of artificial intelligence that can outperform humans. However, there is still much to learn. Here, we leverage the wealth of human PE data acquired in the functional neuroimaging setting in service of a deeper understanding, using meta-analysis. Across 263 PE studies that have focused on reward, punishment, action, cognition, and perception, we found consistent region-PE associations that were posited theoretically or evinced in preclinical studies, but not yet established in humans, including midbrain PE signals during perceptual and Pavlovian tasks. Further, we found evidence for PEs over successor representations in orbitofrontal cortex, and for default mode network PE signals. By combining functional imaging meta-analysis with theory and basic research, we provide new insights into learning in machines, humans, and other animals.


2018 ◽  
Vol 39 (7) ◽  
pp. 2887-2906 ◽  
Author(s):  
Elsa Fouragnan ◽  
Chris Retzler ◽  
Marios G. Philiastides

2019 ◽  
Author(s):  
Hongyu Li ◽  
Jun Li ◽  
Hui Song

Abstract Background: To compare the accuracy of intraocular lens power calculation formulas after refractive surgery in myopic eyes. Methods: We searched the databases on the PubMed, EMBASE, Web of science and Cochrane library to select relevant studies published between Jan 1, 2009 and Aug 11, 2019. Primary outcomes were the percentages of refractive prediction error within ±0.5D and ±1.0D. Results: The results of this meta-analysis were investigated from 16 studies, including 7 common methods (Haigis-L, Shammas-PL, Double-K SRK/T, Barrett true K no history, Wang-Koch-Maloney, ASCRS average and OCT formula). ASCRS average yielded significantly higher percentage of refractive prediction error within ±0.5D than Haigis-L, Shammas-PL and W-K-M (P=0.009, 0.01, 0.008, respectively). Barrett true K no history also yielded significantly higher percentage of refractive prediction error within ±0.5D than Shammas-PL and W-K-M (P=0.01, <0.0001, respectively), and the same result was found by comparing OCT formula with Hiaigi-L and Shammas-PL (P=0.03, 0.01, respectively). Only the Haigis-L had significantly higher percentages than W-K-M method in the ±1.0D group (P = 0.04). Conclusion: We suggest that the ASCRS average and Barrett true K no history formula should be used to calculate the IOL power in eyes after myopic refractive surgery.


2021 ◽  
Vol 8 ◽  
Author(s):  
Yueyang Zhong ◽  
Yibo Yu ◽  
Jinyu Li ◽  
Bing Lu ◽  
Su Li ◽  
...  

Background: Among the various intraocular lens (IOL) power calculation formulas available in clinical settings, which one can yield more accurate results is still inconclusive. We performed a meta-analysis to compare the accuracy of the IOL power calculation formulas used for pediatric cataract patients.Methods: Observational cohort studies published through April 2021 were systematically searched in PubMed, Web of Science, and EMBASE databases. For each included study, the mean differences of the mean prediction error and mean absolute prediction error (APE) were analyzed and compared using the random-effects model.Results: Twelve studies involving 1,647 eyes were enrolled in the meta-analysis, and five formulas were compared: Holladay 1, Holladay 2, Hoffer Q, SRK/T, and SRK II. Holladay 1 exhibited the smallest APE (0.97; 95% confidence interval [CI]: 0.92–1.03). For the patients with an axial length (AL) less than 22 mm, SRK/T showed a significantly smaller APE than SRK II (mean difference [MD]: −0.37; 95% CI: −0.63 to −0.12). For the patients younger than 24 months, SRK/T had a significantly smaller APE than Hoffer Q (MD: −0.28; 95% CI: −0.51 to −0.06). For the patients aged 24–60 months, SRK/T presented a significantly smaller APE than Holladay 2 (MD: −0.60; 95% CI: −0.93 to −0.26).Conclusion: Due to the rapid growth and high variability of pediatric eyes, the formulas for IOL calculation should be considered according to clinical parameters such as age and AL. The evidence obtained supported the accuracy and reliability of SRK/T under certain conditions.Systematic Review Registration: PROSPERO, identifier: INPLASY202190077.


Sign in / Sign up

Export Citation Format

Share Document