Lessons learned from early closure of a clinical trial for steroid-refractory acute GVHD

Author(s):  
Gabrielle Meyers ◽  
Mehdi Hamadani ◽  
Michael Martens ◽  
Haris Ali ◽  
Hannah Choe ◽  
...  
2012 ◽  
Vol 33 (2) ◽  
pp. 291-297 ◽  
Author(s):  
Marlene H. Peters-Lawrence ◽  
Margaret C. Bell ◽  
Lewis L. Hsu ◽  
Ifeyinwa Osunkwo ◽  
Phillip Seaman ◽  
...  

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Aldo Badano

AbstractImaging clinical trials can be burdensome and often delay patient access to novel, high-quality medical devices. Tools for in silico imaging trials have significantly improved in sophistication and availability. Here, I describe some of the principal advantages of in silico imaging trials and enumerate five lessons learned during the design and execution of the first all-in silico virtual imaging clinical trial for regulatory evaluation (the VICTRE study).


2014 ◽  
Vol 12 (1-2) ◽  
pp. 90-91
Author(s):  
L. Kindler ◽  
C. McMullen ◽  
A. Owen-Smith ◽  
S. Honda ◽  
A. Firemark ◽  
...  

2011 ◽  
Vol 32 (5) ◽  
pp. 614-619 ◽  
Author(s):  
Lemuel A. Moyé ◽  
Shelly L. Sayre ◽  
Lynette Westbrook ◽  
Beth C. Jorgenson ◽  
Eileen Handberg ◽  
...  

ESMO Open ◽  
2021 ◽  
pp. 100237
Author(s):  
Luis Castelo-Branco ◽  
Ahmad Awada ◽  
George Pentheroudakis ◽  
Jose Luis Perez-Garcia ◽  
Joaquin Mateo ◽  
...  

2018 ◽  
Vol 16 (4) ◽  
pp. 211-212 ◽  
Author(s):  
Trijn Israels ◽  
◽  
Elizabeth M. Molyneux

2019 ◽  
Vol 5 (5) ◽  
pp. 849-852
Author(s):  
Peter F.A. Mulders ◽  
Luis Martínez-Piñeiro ◽  
Axel Heidenreich ◽  
Marko Babjuk ◽  
Marc Colombel ◽  
...  

Case Studies Within Psychotherapy Trials: Integrating Qualitative and Quantitative Methods presents a specific, mixed-methods approach, called the “Cases Within Trials” (CWT) model, to psychotherapy research, combining the results from a randomized clinical trial (RCT) with systematic case studies involving contrasting outcomes drawn from the experimental condition of the RCT; and a synthesis of the two types of knowledge. Chapters 3–6 of the book present four specific and diverse projects that concretely illustrate the CWT method. In Chapter 8 the editors analyze the four chapters and explore emergent themes in the knowledge gained from them. In the process, the editors systematically compare the positive-outcome and negative-outcome cases across the four projects, highlighting, for example, (a) the importance of contextual variables in creating the conditions for change mechanisms to be activated; (b) the multidimensional, reciprocally interactional nature of the therapy process; and (c) the particular role of therapist responsiveness.


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