scholarly journals Brain stimulation and brain lesions converge on common causal circuits in neuropsychiatric disease

Author(s):  
Shan H. Siddiqi ◽  
Frederic L. W. V. J. Schaper ◽  
Andreas Horn ◽  
Joey Hsu ◽  
Jaya L. Padmanabhan ◽  
...  
2021 ◽  
Author(s):  
José Damián Carrillo-Ruíz ◽  
Jesús Quetzalcoatl Beltran ◽  
José Rodrigo Carrillo-Márquez ◽  
José Luis Navarro-Olvera ◽  
Luis García ◽  
...  

Spasticity is one of the most important and residual signs after pyramidal and para-pyramidal catastrophic lesions after diverse neurological insults, including stroke, brain and spine trauma and post-radiation; infection and immunological diseases affecting nervous system, between others. Spasticity is normally a compensatory motor mechanism that could ameliorate the patients´ disability. Nevertheless, disastrous spasticity is described when the extremities force is diminished in the affected limbs, or when is impossible to wake o to take objects, maximum when hand or foot deformity is exposed. The objective of this chapter is centered in the neurosurgical treatment of spasticity, including brain lesions with specific targets and the spine with its different modalities. This review shows not only the basic aspects in these techniques, but also the option of infusion pumps and deep brain stimulation. To close, a proposal is stablished to determinate the possible path to treat the spasticity in the future.


2021 ◽  
Vol 14 (6) ◽  
pp. 1643-1644
Author(s):  
Frederic Schaper ◽  
Janne Nordberg ◽  
Alexander Cohen ◽  
Joey Hsu ◽  
Christopher Lin ◽  
...  

2018 ◽  
Vol 75 (7) ◽  
pp. 448-454
Author(s):  
Thomas Grunwald ◽  
Judith Kröll

Zusammenfassung. Wenn mit den ersten beiden anfallspräventiven Medikamenten keine Anfallsfreiheit erzielt werden konnte, so ist die Wahrscheinlichkeit, dies mit anderen Medikamenten zu erreichen, nur noch ca. 10 %. Es sollte dann geprüft werden, warum eine Pharmakoresistenz besteht und ob ein epilepsiechirurgischer Eingriff zur Anfallsfreiheit führen kann. Ist eine solche Operation nicht möglich, so können palliative Verfahren wie die Vagus-Nerv-Stimulation (VNS) und die tiefe Hirnstimulation (Deep Brain Stimulation) in eine bessere Anfallskontrolle ermöglichen. Insbesondere bei schweren kindlichen Epilepsien stellt auch die ketogene Diät eine zu erwägende Option dar.


1981 ◽  
Vol 26 (8) ◽  
pp. 641-642 ◽  
Author(s):  
James C. Reed
Keyword(s):  

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