Structural basis for ligand reception by anaplastic lymphoma kinase

Nature ◽

10.1038/s41586-021-04141-7 ◽

2021 ◽

Author(s):

Tongqing Li ◽

Steven E. Stayrook ◽

Yuko Tsutsui ◽

Jianan Zhang ◽

Yueyue Wang ◽

...

Keyword(s):

Anaplastic Lymphoma Kinase ◽

Structural Basis ◽

Anaplastic Lymphoma

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Structural basis for drug resistance mechanisms against anaplastic lymphoma kinase

Journal of Cellular Biochemistry ◽

10.1002/jcb.27437 ◽

2018 ◽

Vol 120 (1) ◽

pp. 768-777 ◽

Author(s):

Sukriti Goyal ◽

Salma Jamal ◽

Asheesh Shanker ◽

Abhinav Grover

Keyword(s):

Drug Resistance ◽

Anaplastic Lymphoma Kinase ◽

Resistance Mechanisms ◽

Structural Basis ◽

Anaplastic Lymphoma

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Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2

Journal of Structural and Functional Genomics ◽

10.1007/s10969-010-9091-x ◽

2010 ◽

Vol 11 (2) ◽

pp. 125-141 ◽

Author(s):

Seizo Koshiba ◽

Hua Li ◽

Yoko Motoda ◽

Tadashi Tomizawa ◽

Takuma Kasai ◽

...

Keyword(s):

Neurotrophic Factor ◽

Anaplastic Lymphoma Kinase ◽

Binding Domain ◽

Structural Basis ◽

Anaplastic Lymphoma ◽

Phosphotyrosine Binding Domain

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Regulated expression of the Anaplastic Lymphoma Kinase (ALK) in cultured rat hepatic stellate cells during transdifferentiation into myofibroblasts

Zeitschrift für Gastroenterologie ◽

10.1055/s-2005-861584 ◽

2005 ◽

Vol 43 (01) ◽

Author(s):

M Antoine ◽

CG Tag ◽

W Wirz ◽

M Mavituna ◽

AM Gressner ◽

...

Keyword(s):

Hepatic Stellate Cells ◽

Anaplastic Lymphoma Kinase ◽

Stellate Cells ◽

Anaplastic Lymphoma ◽

Regulated Expression

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Anaplastic Lymphoma Kinase in Human Cancer

Critical Reviews™ in Oncogenesis ◽

10.1615/critrevoncog.v17.i2.10 ◽

2012 ◽

Vol 17 (2) ◽

pp. 123-143 ◽

Author(s):

Christina Schonherr ◽

Bengt Hallberg ◽

Ruth Palmer

Keyword(s):

Anaplastic Lymphoma Kinase ◽

Human Cancer ◽

Anaplastic Lymphoma

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Study of TQ-B3139 Versus Crizotinib in the First Line Treatment of Subjects With Anaplastic Lymphoma Kinase (ALK) Positive Non-Small Cell Lung Cancer (NSCLC)

Case Medical Research ◽

10.31525/ct1-nct04009317 ◽

2019 ◽

Author(s):

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Line Treatment ◽

Small Cell Lung ◽

Anaplastic Lymphoma ◽

Alk Positive ◽

First Line Treatment

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Faculty Opinions recommendation of Anaplastic lymphoma kinase spares organ growth during nutrient restriction in Drosophila.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12593957.791402800 ◽

2012 ◽

Author(s):

Savraj Grewal

Keyword(s):

Anaplastic Lymphoma Kinase ◽

Nutrient Restriction ◽

Organ Growth ◽

Anaplastic Lymphoma

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Faculty Opinions recommendation of The anaplastic lymphoma kinase in the pathogenesis of cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13353985.14725086 ◽

2011 ◽

Author(s):

Ruth Palmer

Keyword(s):

Anaplastic Lymphoma Kinase ◽

Anaplastic Lymphoma

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Faculty Opinions recommendation of Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12934957.14822055 ◽

2012 ◽

Author(s):

John Proudfoot

Keyword(s):

Drug Design ◽

Anaplastic Lymphoma Kinase ◽

Dual Inhibitor ◽

Structure Based Drug Design ◽

Anaplastic Lymphoma ◽

Mesenchymal Epithelial Transition Factor ◽

Factor C ◽

Mesenchymal Epithelial Transition

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Faculty Opinions recommendation of Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12934957.14323054 ◽

2011 ◽

Author(s):

John Lowe

Keyword(s):

Drug Design ◽

Anaplastic Lymphoma Kinase ◽

Dual Inhibitor ◽

Structure Based Drug Design ◽

Anaplastic Lymphoma ◽

Mesenchymal Epithelial Transition Factor ◽

Factor C ◽

Mesenchymal Epithelial Transition

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Faculty Opinions recommendation of Design of potent and selective inhibitors to overcome clinical anaplastic lymphoma kinase mutations resistant to crizotinib.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718242031.793491637 ◽

2014 ◽

Author(s):

Jürgen Bajorath

Keyword(s):

Anaplastic Lymphoma Kinase ◽

Selective Inhibitors ◽

Anaplastic Lymphoma

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