scholarly journals Pulmonary rehabilitation improves survival in patients with idiopathic pulmonary fibrosis undergoing lung transplantation

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Juliessa Florian ◽  
Guilherme Watte ◽  
Paulo José Zimermann Teixeira ◽  
Stephan Altmayer ◽  
Sadi Marcelo Schio ◽  
...  
2018 ◽  
Vol 38 (2) ◽  
pp. 131-134 ◽  
Author(s):  
Fabrício Farias da Fontoura ◽  
Danilo Cortozi Berton ◽  
Guilherme Watte ◽  
Juliessa Florian ◽  
Sadi Marcelo Schio ◽  
...  

2021 ◽  
Vol 10 (16) ◽  
pp. 3474
Author(s):  
Belén López-Muñiz Ballesteros ◽  
Marta López-Herranz ◽  
Ana Lopez-de-Andrés ◽  
Valentín Hernandez-Barrera ◽  
Rodrigo Jiménez-García ◽  
...  

(1) Background: To assess sex differences in the incidence, characteristics, procedures and outcomes of patients admitted with idiopathic pulmonary fibrosis (IPF); and to analyze variables associated with in-hospital mortality (IHM). (2) Methods: We analyzed data collected by the Spanish National Hospital Discharge Database, 2016–2019. (3) Results: We identified 13,278 hospital discharges (66.4% men) of IPF (primary diagnosis 32.33%; secondary diagnosis: 67.67%). Regardless of the diagnosis position, IPF incidence was higher among men than women, increasing with age. Men had 2.74 times higher IPF incidence than women. Comorbidity was higher for men in either primary or secondary diagnosis. After matching, men had higher prevalence of pulmonary embolism and pneumonia, and women of congestive heart failure, dementia, rheumatoid disease and pulmonary hypertension. Invasive ventilation, bronchoscopy and lung transplantation were received more often by men than women. IHM was higher among men with IPF as primary diagnosis than among women and increased with age in both sexes and among those who suffered cancer, pneumonia or required mechanical ventilation. (4) Conclusions: Incidence of IPF was higher among men than women, as well as comorbidity and use of bronchoscopy, ventilation and lung transplantation. IHM was worse among men than women with IPF as primary diagnosis, increasing with age, cancer, pneumonia or mechanical ventilation use.


2021 ◽  
Vol 28 (5) ◽  
pp. 987
Author(s):  
Mustafa Vayvada ◽  
Ayse Halis ◽  
Pinar Guney ◽  
Sevinc Citak ◽  
Ali Yiginsu ◽  
...  

Author(s):  
Jonathan K. Alder ◽  
Rachel M. Sutton ◽  
Carlo J. Iasella ◽  
Mehdi Nouraie ◽  
Ritchie Koshy ◽  
...  

2018 ◽  
Vol 38 (5) ◽  
pp. 273-278 ◽  
Author(s):  
Mansueto Gomes-Neto ◽  
Cassio Magalhães Silva ◽  
Diego Ezequiel ◽  
Cristiano Sena Conceição ◽  
Micheli Saquetto ◽  
...  

2021 ◽  
pp. 2004053
Author(s):  
Amisha V. Barochia ◽  
Maryann Kaler ◽  
Nargues Weir ◽  
Elizabeth M. Gordon ◽  
Debbie M. Figueroa ◽  
...  

BackgroundSerum lipoproteins, such as high density lipoproteins (HDL), may influence disease severity in idiopathic pulmonary fibrosis (IPF). Here, we investigated associations between serum lipids and lipoproteins and clinical endpoints in IPF.MethodsClinical data and serum lipids were analyzed from a discovery cohort (59 IPF subjects, 56 healthy volunteers) and validated using an independent, multicenter cohort (207 IPF subjects) from the Pulmonary Fibrosis Foundation registry. Associations between lipids and clinical endpoints (FVC, forced vital capacity; 6MWD, 6 min walk distance; GAP (Gender Age Physiology) index; death or lung transplantation) were examined using Pearson's correlation and multivariable analyses.ResultsSerum concentrations of small HDL particles (S-HDLPNMR), measured by nuclear magnetic resonance (NMR) spectroscopy, correlated negatively with the GAP index in the discovery cohort of IPF subjects. The negative correlation of S-HDLPNMR with GAP index was confirmed in the validation cohort of IPF subjects. Higher levels of S-HDLPNMR were associated with lower odds of death or its competing outcome, lung transplantation (OR of 0.9 for each 1 μmol·L−1 increase in S-HDLPNMR, p<0.05), at 1, 2, and 3 years from study entry in a combined cohort of all IPF subjects.ConclusionsHigher serum levels of S-HDLPNMR are negatively correlated with the GAP index, as well as with lower observed mortality or lung transplantation in IPF subjects. These findings support the hypothesis that S-HDLPNMR may modify mortality risk in patients with IPF.


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