scholarly journals Detection and classification of intracranial haemorrhage on CT images using a novel deep-learning algorithm

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Ji Young Lee ◽  
Jong Soo Kim ◽  
Tae Yoon Kim ◽  
Young Soo Kim

AbstractA novel deep-learning algorithm for artificial neural networks (ANNs), completely different from the back-propagation method, was developed in a previous study. The purpose of this study was to assess the feasibility of using the algorithm for the detection of intracranial haemorrhage (ICH) and the classification of its subtypes, without employing the convolutional neural network (CNN). For the detection of ICH with the summation of all the computed tomography (CT) images for each case, the area under the ROC curve (AUC) was 0.859, and the sensitivity and the specificity were 78.0% and 80.0%, respectively. Regarding ICH localisation, CT images were divided into 10 subdivisions based on the intracranial height. With the subdivision of 41–50%, the best diagnostic performance for detecting ICH was obtained with AUC of 0.903, the sensitivity of 82.5%, and the specificity of 84.1%. For the classification of the ICH to subtypes, the accuracy rate for subarachnoid haemorrhage (SAH) was considerably excellent at 91.7%. This study revealed that our approach can greatly reduce the ICH diagnosis time in an actual emergency situation with a fairly good diagnostic performance.

Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1615
Author(s):  
Ines P. Nearchou ◽  
Hideki Ueno ◽  
Yoshiki Kajiwara ◽  
Kate Lillard ◽  
Satsuki Mochizuki ◽  
...  

The categorisation of desmoplastic reaction (DR) present at the colorectal cancer (CRC) invasive front into mature, intermediate or immature type has been previously shown to have high prognostic significance. However, the lack of an objective and reproducible assessment methodology for the assessment of DR has been a major hurdle to its clinical translation. In this study, a deep learning algorithm was trained to automatically classify immature DR on haematoxylin and eosin digitised slides of stage II and III CRC cases (n = 41). When assessing the classifier’s performance on a test set of patient samples (n = 40), a Dice score of 0.87 for the segmentation of myxoid stroma was reported. The classifier was then applied to the full cohort of 528 stage II and III CRC cases, which was then divided into a training (n = 396) and a test set (n = 132). Automatically classed DR was shown to have superior prognostic significance over the manually classed DR in both the training and test cohorts. The findings demonstrated that deep learning algorithms could be applied to assist pathologists in the detection and classification of DR in CRC in an objective, standardised and reproducible manner.


2021 ◽  
Vol 237 ◽  
pp. 106718
Author(s):  
Sepideh Alsadat Azimi ◽  
Hossein Afarideh ◽  
Jong-Seo Chai ◽  
Martin Kalinowski ◽  
Abdelhakim Gheddou ◽  
...  

Author(s):  
Konstantinos Exarchos ◽  
Dimitrios Potonos ◽  
Agapi Aggelopoulou ◽  
Agni Sioutkou ◽  
Konstantinos Kostikas

2021 ◽  
Author(s):  
Noreen Anwar ◽  
Zhen Shen ◽  
Qinglai Wei ◽  
Gang Xiong ◽  
Peijun Ye ◽  
...  

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