scholarly journals Low expression of polypeptide GalNAc N-acetylgalactosaminyl transferase-3 in lung adenocarcinoma: impact on poor prognosis and early recurrence

2004 ◽  
Vol 90 (2) ◽  
pp. 436-442 ◽  
Author(s):  
C Gu ◽  
T Oyama ◽  
T Osaki ◽  
J Li ◽  
M Takenoyama ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Poor Prognosis ◽  
Early Recurrence ◽  
Low Expression

Low expression of RGL4 is associated with a poor prognosis and immune infiltration in lung adenocarcinoma patients

2020 ◽  
Vol 83 ◽  
pp. 106454 ◽  
Author(s):  
Yidan Sun ◽  
Ying Zhang ◽  
Shiqi Ren ◽  
Xiaojiang Li ◽  
Peiying Yang ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Poor Prognosis ◽  
Immune Infiltration ◽  
Low Expression

P-147 Low expression of polypeptide N-acetyl-galactosaminyl transferase-3 (GaINAc-T3) is associated with pathological differentiation and poor prognosis in lung adenocarcinoma

Lung Cancer ◽  
2003 ◽  
Vol 41 ◽  
pp. S127
Author(s):  
Kenji Sugio ◽  
Tsunehiro Oyama ◽  
Toshihiro Osaki ◽  
Takeshi Hanagiri ◽  
Mitsuhiro Takenoyama ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Poor Prognosis ◽  
Pathological Differentiation ◽  
Low Expression

scholarly journals Low expression lncRNA RPLP0P2 is associated with poor prognosis and decreased cell proliferation and adhesion ability in lung adenocarcinoma

2016 ◽  
Vol 36 (3) ◽  
pp. 1665-1671 ◽  
Author(s):  
Jie Chen ◽  
Lijuan Hu ◽  
Jian Chen ◽  
Fang Wu ◽  
Dongwei Hu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Lung Adenocarcinoma ◽  
Poor Prognosis ◽  
Adhesion Ability ◽  
Low Expression

scholarly journals Low expression of NLRP1 is associated with a poor prognosis and immune infiltration in lung adenocarcinoma patients

Aging ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 7570-7588
Author(s):  
Edward Shen ◽  
Ying Han ◽  
Changjing Cai ◽  
Ping Liu ◽  
Yihong Chen ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Poor Prognosis ◽  
Immune Infiltration ◽  
Low Expression

scholarly journals Low expression of IL6R predicts poor prognosis for lung adenocarcinoma

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Gaofeng Sun ◽  
Tianyi Wang ◽  
Muqi Shi ◽  
Hao Zhou ◽  
Jinjie Wang ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Poor Prognosis ◽  
Low Expression

scholarly journals Impact of the micropapillary component on the timing of recurrence in patients with resected lung adenocarcinoma

2020 ◽  
Vol 58 (5) ◽  
pp. 1010-1018 ◽  
Author(s):  
Katsuya Watanabe ◽  
Kentaro Sakamaki ◽  
Hiroyuki Ito ◽  
Tomoyuki Yokose ◽  
Kozo Yamada ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Poor Prognosis ◽  
Cox Regression ◽  
Postoperative Recurrence ◽  
Early Recurrence ◽  
Stage I ◽  
Hazard Curves ◽  
And Gender ◽  
The Impact

Abstract OBJECTIVES A micropapillary (MIP) component is reported to be associated with a poor prognosis in patients with completely resected lung adenocarcinoma. The purpose of this study was to investigate the impact of an MIP component on the timing of postoperative recurrence using hazard curves. METHODS A total of 1289 patients with lung adenocarcinoma who underwent complete pulmonary resection from 2008 to 2015 were studied. Hazard curves representing the changes in hazard over time were evaluated. RESULTS The hazard curve displayed an initial wide, high peak within 1 year after surgery in patients with an MIP component, whereas some gentle peaks around the second year were noted in patients without an MIP component. The presence of an MIP component was associated with a worse recurrence-free survival and an early recurrence in stage I patients but not in advanced-stage patients. In multivariable Cox regression, the presence of an MIP component and lymph node metastasis, pleural invasion and gender were associated with a poor prognosis. CONCLUSIONS Patients with an MIP component retained a high risk of early recurrence after surgery, and the risk for recurrence persisted over the long term. Even after complete resection in stage I lung adenocarcinoma patients, an MIP component remains correlated with a poor prognosis.

miR-224 is an early-stage biomarker of hepatocellular carcinoma with miR-224 and miR-125b as prognostic biomarkers

2020 ◽  
Vol 14 (15) ◽  
pp. 1485-1500
Author(s):  
Lichao Yang ◽  
Chunmeng Wei ◽  
Yasi Li ◽  
Xiao He ◽  
Min He
Keyword(s):  
Hepatocellular Carcinoma ◽  
Systematic Review ◽  
Survival Analysis ◽  
Sensitivity And Specificity ◽  
Poor Prognosis ◽  
Early Stage ◽  
Meta Analysis ◽  
Benign Lesion ◽  
Diagnostic Efficiency ◽  
Low Expression

Aim: The aim was to systematically investigate the miRNA biomarkers for early diagnosis of hepatocellular carcinoma (HCC). Materials & methods: A systematic review and meta-analysis of miRNA expression in HCC were performed. Results: A total of 4903 cases from 30 original studies were comprehensively analyzed. The sensitivity and specificity of miR-224 in discriminating early-stage HCC patients from benign lesion patients were 0.868 and 0.792, which were superior to α-fetoprotein. Combined miR-224 with α-fetoprotein, the sensitivity and specificity were increased to 0.882 and 0.808. Prognostic survival analysis showed low expression of miR-125b and high expression of miR-224 were associated with poor prognosis. Conclusion: miR-224 had a prominent diagnostic efficiency in early-stage HCC, with miR-224 and miR-125b being valuable in the prognostic diagnosis.

scholarly journals Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation

Lung Cancer ◽  
2021 ◽  
Author(s):  
Pablo Moreno-Ruiz ◽  
Sara Corvigno ◽  
Nienke C. te Grootenhuis ◽  
Linnéa La Fleur ◽  
Max Backman ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Poor Prognosis ◽  
P53 Mutation ◽  
Small Cell ◽  
Small Cell Lung ◽  
Prognosis Marker
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