scholarly journals Characterization of the effects of isoprostanes on platelet aggregation in human whole blood

2001 ◽  
Vol 132 (8) ◽  
pp. 1699-1706 ◽  
Author(s):  
Julius H Cranshaw ◽  
Timothy W Evans ◽  
Jane A Mitchell
Keyword(s):  
Platelet Aggregation ◽  
Whole Blood ◽  
Human Whole Blood

scholarly journals Isolation and characterization of circulating pro-vascular progenitor cell subsets from human whole blood samples

2021 ◽  
Vol 2 (1) ◽  
pp. 100311
Author(s):  
Daniella C. Terenzi ◽  
Ehab Bakbak ◽  
Justin Z. Trac ◽  
Mohammad Al-Omran ◽  
Adrian Quan ◽  
...  
Keyword(s):  
Whole Blood ◽  
Progenitor Cell ◽  
Blood Samples ◽  
Human Whole Blood ◽  
Isolation And Characterization ◽  
Whole Blood Samples

Effect of prenylated flavonoids and chalcones isolated from Artocarpus species on platelet aggregation in human whole blood

2010 ◽  
Vol 64 (3) ◽  
pp. 365-369 ◽  
Author(s):  
Ibrahim Jantan ◽  
Yusyila H. Mohd Yasin ◽  
Shajarahtunnur Jamil ◽  
Hasnah Sirat ◽  
Norazah Basar
Keyword(s):  
Platelet Aggregation ◽  
Whole Blood ◽  
Human Whole Blood ◽  
Prenylated Flavonoids

Endotoxin-Induced Platelet Activation in Human Whole Blood In Vitro

1988 ◽  
Vol 59 (03) ◽  
pp. 378-382 ◽  
Author(s):  
Gyorgy Csako ◽  
Eva A Suba ◽  
Ronald J Elin
Keyword(s):  
Platelet Aggregation ◽  
Whole Blood ◽  
Human Platelet ◽  
Platelet Rich Plasma ◽  
Atp Release ◽  
Human Platelets ◽  
Lag Phase ◽  
Human Whole Blood ◽  
Dose Dependent

SummaryThe effect of purified bacterial endotoxin was studied on human platelets in vitro. In adding up to 1 μg/mL of a highly purified endotoxin, we found neither aggregation nor ATP release in heparinized or citrated human platelet-rich plasma. On the other hand, endotoxin at concentrations as low as a few ng/mL (as may be found in septic patients) caused platelet aggregation in both heparinized and citrated human whole blood, as monitored by change in impedance, free platelet count, and size. Unlike collagen, the platelet aggregation with endotoxin occurred after a long lag phase, developed slowly, and was rarely coupled with measurable release of ATP. The platelet aggregating effect of endotoxin was dose-dependent and modified by exposure of the endotoxin to ionizing radiation. Thus, the activation of human platelets by “solubilized” endotoxin in plasma requires the presence of other blood cells. We propose that the platelet effect is mediated by monocytes and/or neutrophils stimulated by endotoxin.

Characterization of microvesicles released from human whole blood after incubation with Bothrops jararaca venom: An in vitro preliminary study

Toxicon ◽  
2020 ◽  
Vol 177 ◽  
pp. S31
Author(s):  
Milene Cristina Menezes ◽  
DIlza Trevisan-Silva ◽  
Daniela Cajado-Carvalho ◽  
Solange Serrano
Keyword(s):  
Whole Blood ◽  
Human Whole Blood ◽  
Bothrops Jararaca ◽  
Preliminary Study

Platelet aggregation in human whole blood after chronic administration of aspirin

1987 ◽  
Vol 46 (1) ◽  
pp. 133-140 ◽  
Author(s):  
J.P. De La Cruz ◽  
S. Camara ◽  
I. Bellido ◽  
T. Carrasco ◽  
F.Sanchez De La Cuesta
Keyword(s):  
Platelet Aggregation ◽  
Whole Blood ◽  
Chronic Administration ◽  
Human Whole Blood
Sign in / Sign up

Export Citation Format

Share Document