Antitumor activity of 2-fluoro-2′-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase

Purine Nucleoside ◽

6-Methylpurine derived sugar modified nucleosides: Synthesis and in vivo antitumor activity in D54 tumor expressing M64V- Escherichia coli purine nucleoside phosphorylase

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2015.12.029 ◽

2016 ◽

Vol 108 ◽

pp. 616-622 ◽

Cited By ~ 2

Author(s):

Abdalla E.A. Hassan ◽

Reham A.I. Abou-Elkhair ◽

William B. Parker ◽

Paula W. Allan ◽

John A. Secrist

Keyword(s):

Escherichia Coli ◽

Antitumor Activity ◽

Modified Nucleosides ◽

Purine Nucleoside ◽

In Vivo Antitumor Activity

High-temperature cultivation and 5′ mRNA optimization are key factors for the efficient overexpression of thermostable Deinococcus geothermalis purine nucleoside phosphorylase in Escherichia coli

Journal of Biotechnology ◽

10.1016/j.jbiotec.2011.08.009 ◽

2011 ◽

Vol 156 (4) ◽

pp. 268-274 ◽

Cited By ~ 6

Author(s):

Kathleen Szeker ◽

Olli Niemitalo ◽

Marco G. Casteleijn ◽

André H. Juffer ◽

Peter Neubauer

Keyword(s):

Escherichia Coli ◽

High Temperature ◽

Purine Nucleoside ◽

Key Factors ◽

Deinococcus Geothermalis

2-Chloro-2' -deoxyadenosine (Cladribine) and its Analogues are Good Substrates and Potent Selective Inhibitors of Escherichia coli Purine-Nucleoside Phosphorylase

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1995.886_3.x ◽

1995 ◽

Vol 233 (3) ◽

pp. 886-890 ◽

Cited By ~ 9

Author(s):

Agnieszka Bzowska ◽

Zygmunt Kazimierczuk

Keyword(s):

Escherichia Coli ◽

Purine Nucleoside ◽

Selective Inhibitors ◽

Synthesis of 3′-α-fluoronucleosides Using Pyrimidine Nucleoside Phosphorylase of Thermus thermophilus and Purine Nucleoside Phosphorylase of Escherichia coli

Life Chemistry Research ◽

10.1201/b18527-23 ◽

2015 ◽

pp. 191-200

Keyword(s):

Escherichia Coli ◽

Thermus Thermophilus ◽

Purine Nucleoside ◽

Pyrimidine Nucleoside ◽

Pyrimidine Nucleoside Phosphorylase

Antitumor effects of a dual-specific lentiviral vector carrying the Escherichia coli purine nucleoside phosphorylase gene

International Journal of Oncology ◽

10.3892/ijo.2017.3949 ◽

2017 ◽

Vol 50 (5) ◽

pp. 1612-1622

Author(s):

Xiaolong Wang ◽

Lei Sun ◽

Xuejun Sun ◽

Junhui Yu ◽

Kai Wang ◽

...

Keyword(s):

Escherichia Coli ◽

Lentiviral Vector ◽

Purine Nucleoside ◽

Antitumor Effects ◽

Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene

Cancer Gene Therapy ◽

10.1038/cgt.2010.17 ◽

2010 ◽

Vol 17 (9) ◽

pp. 614-623 ◽

Cited By ~ 25

Author(s):

C-K Tai ◽

W Wang ◽

Y-H Lai ◽

C R Logg ◽

W B Parker ◽

...

Keyword(s):

Escherichia Coli ◽

Purine Nucleoside ◽

Prodrug Activation ◽

Activation Therapy ◽

Tumor Selective

Erratum: Targeted expression of Escherichia coli purine nucleoside phosphorylase and Fludara® for prostate cancer therapy

The Journal of Gene Medicine ◽

10.1002/jgm.2617 ◽

2012 ◽

Vol 14 (3) ◽

pp. 217-217

Author(s):

Xinhua Xie ◽

Jiaoli Guo ◽

Yanan Kong ◽

Gene Xianquan Xie ◽

Laishen Li ◽

...

Keyword(s):

Prostate Cancer ◽

Escherichia Coli ◽

Cancer Therapy ◽

Purine Nucleoside ◽

Prostate Cancer Therapy ◽

Targeted Expression

Purine-Nucleoside Phosphorylase from Salmonella typhimurium and Escherichia coli. Initial Velocity Kinetics, Ligand Binding, and Reaction Mechanism

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1976.tb10031.x ◽

1976 ◽

Vol 61 (2) ◽

pp. 377-386 ◽

Cited By ~ 28

Author(s):

Kaj Frank JENSEN

Keyword(s):

Escherichia Coli ◽

Reaction Mechanism ◽

Ligand Binding ◽

Salmonella Typhimurium ◽

Initial Velocity ◽

Purine Nucleoside ◽

18. Comparison of Antitumor Activity of Cytosine Deaminase::Uracil Phosphoribosyl Transferase (CD::UPRT) and Purine Nucleoside Phosphorylase (PNP) Suicide Genes Using Replicative but Non-Disseminative Adenovirus Vectors

Molecular Therapy ◽

10.1016/j.ymthe.2006.08.029 ◽

2006 ◽

Vol 13 ◽

pp. S8

Author(s):

Jairo Jaime ◽

Nadine Jabbour ◽

William Parker ◽

Eric Sorscher ◽

Josephine Nalbantoglu ◽

...

Keyword(s):

Antitumor Activity ◽

Cytosine Deaminase ◽

Purine Nucleoside ◽

Suicide Genes ◽

Phosphoribosyl Transferase ◽

Adenovirus Vectors

ChemInform Abstract: Synthesis of 8-Amino-3-deazaguanine via Imidazole Precursors. Antitumor Activity and Inhibition of Purine Nucleoside Phosphorylase.

ChemInform ◽

10.1002/chin.198711190 ◽

1987 ◽

Vol 18 (11) ◽

Author(s):

D. A. BERRY ◽

R. B. GILBERTSEN ◽

P. D. COOK

Keyword(s):

Antitumor Activity ◽

Purine Nucleoside ◽