Quality of life of primary caregivers of spinal cord injury survivors living in the community: controlled study with short form-36 questionnaire

Background. A spinal cord injury (SCI) leads to patho-physiological changes that can affect physical and psychological performance. The aim of this observational study was to evaluate the relationship between exercise capacity, functioning and quality of life in patients 12 weeks after traumatic paraplegia participating in early rehabilitation. Material and methods. 13 patients participated in this study and performed cardio-pulmonary exercise testing (CPET) on an arm-crank ergometer to determine peak exercise capacity (VO2peak). Data from the spinal cord independence measure (SCIM) were used to assess different areas of functioning. The 12-item short form survey (SF12) questionnaire was applied to measure quality of life. Spearman correlations were used to relate VO2peak with SCIM data and results from the SF12 questionnaire. Results. VO2peak ranged between 12.6 and 28.1 ml/kg/min. A significant relationship was found between VO2peak and the physical component of the SF12 questionnaire, whereas no correlations were found with either SCIM sub or total score, or with the mental component or the total score of the SF12 questionnaire. Conclusions. 1. Patients with traumatic paraplegia showed fair to average exercise capacity after 12 weeks of early rehabilitation. 2. A significant relationship between VO2peak and subjectively rated physical fitness exists at this time point. 3. The implementation of an individual fitness program tailored to the patients' needs based on CPET results is highly recommended in order to improve functioning and quality of life.

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Qualiveen Italian Validation: A Long and Short Form Quality of Life Questionnaire in Patients with Spinal Cord Injury and Urinary Disorders

UroToday International Journal ◽

10.3834/uij.1939-4810.2008.06.61 ◽

2008 ◽

Author(s):

Giulio Del Popolo

Keyword(s):

Quality Of Life ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Short Form ◽

Life Questionnaire ◽

Quality Of Life Questionnaire ◽

Italian Validation ◽

Cord Injury ◽

Form Quality

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The effects of using the internet on the health-related quality of life in people with spinal cord injury: a controlled study

Spinal Cord ◽

10.1038/sc.2014.7 ◽

2014 ◽

Vol 52 (5) ◽

pp. 388-391 ◽

Cited By ~ 3

Author(s):

B Celik ◽

K Ones ◽

E C Celik ◽

D S Bugdayci ◽

N Paker ◽

...

Keyword(s):

Quality Of Life ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Controlled Study ◽

The Internet ◽

Health Related Quality ◽

Cord Injury ◽

Related Quality ◽

Health Related

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‘Quality of life of primary caregivers of children with cerebral palsy: a controlled study with Short Form-36 questionnaire’

Developmental Medicine & Child Neurology ◽

10.1111/j.1469-8749.2004.tb01031.x ◽

2007 ◽

Vol 46 (9) ◽

pp. 647-648 ◽

Cited By ~ 14

Author(s):

Hakan Tuna ◽

Halil Ünalan ◽

Filiz Tuna ◽

Siren Kokino

Keyword(s):

Quality Of Life ◽

Cerebral Palsy ◽

Short Form ◽

Primary Caregivers ◽

Controlled Study ◽

Short Form 36 ◽

Children With Cerebral Palsy

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Analgesic Effect of Bumetanide on Neuropathic Pain in Patients with Spinal Cord Injury

Basic and Clinical Neuroscience Journal ◽

10.32598/bcn.2021.2049.1 ◽

2021 ◽

Author(s):

Farinaz Nasirinezhad ◽

◽

Leila Zarepour ◽

Mahmoudreza Hadjighassem ◽

Zeinab Gharaylou ◽

...

Keyword(s):

Quality Of Life ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Neuropathic Pain ◽

Analgesic Effect ◽

Short Form ◽

Mcgill Pain Questionnaire ◽

Pain Questionnaire ◽

Cord Injury

Objectives: The current study evaluated the analgesic effects of bumetanide as an adjunctive treatment in the management of neuropathic pain following spinal cord injury. The peripheral expression of Na-K-Cl-cotransporter-1 1 and K-Cl-cotransporter-2 (KCC2)2 genes in polymorphonuclear lymphocytes (PMLs) assessed as a possible biomarker indicating central mechanisms underlying the observed response. Methods: Through an open-label, single arm, pilot trial of bumetanide (2mg/day), as add-on treatment conducted in 14 SCI patients for 19 weeks. This study consisted of 3 phases: pre-treatment (1month), titration (3 weeks), and active treatment (4 months). Ultimately, 9 patients completed the study. The primary outcome variables were the endpoint pain score using the numeric rating scale (NRS), and also the short-form McGill Pain Questionnaire. Secondary endpoints included the Short-Form Health Survey that assesses the quality of life. Blood samples were collected and used for determining the expression of NKCC1 and KCC2 genes in transcription and translation levels. Results: Bumetanide treatment significantly decreased average pain intensity according to the NRS and the short form of the McGill Pain Questionnaire scores. Baseline expression of KCC2 protein was low between groups and increased significantly following treatment (P<0.05). In the current study, pain improvement accompanied by the greater mean change from the baseline (improvement) for the overall quality of life. Conclusions: These data highlighted the analgesic effect of bumetanide on neuropathic pain and indicated the probable role of upregulation of KCC2 protein and involvement of GABAergic disinhibition in producing neuropathic pain.

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GH deficiency in patients with spinal cord injury: efficacy/safety of GH replacement, a pilot study

Endocrine Connections ◽

10.1530/ec-18-0296 ◽

2018 ◽

Vol 7 (10) ◽

pp. 1031-1039 ◽

Cited By ~ 5

Author(s):

Guillem Cuatrecasas ◽

Hatice Kumru ◽

M Josep Coves ◽

Joan Vidal

Keyword(s):

Quality Of Life ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Physical Therapy ◽

Gh Deficiency ◽

Controlled Study ◽

Gh Secretion ◽

Gh Replacement ◽

Cord Injury

Objective Growth hormone (GH) was shown to stimulate proliferation, migration and survival of neural cells in animal models. GH deficiency (GHD) was reported following traumatic brain lesions; however, there are not available data in spinal cord injury (SCI) patients. The aim of the study was to evaluate (1) the frequency of GHD in chronic SCI population; (2) the efficacy/safety of GH replacement in patients with SCI and suboptimal GH secretion. Design and methods Nineteen consecutive patients with chronic thoracic complete SCI (AIS-A) were studied. Patients with low GH secretion were randomized in a double-blind, placebo-controlled study to receive either subcutaneous placebo injections or GH combined with physical therapy, for 6 months. Baseline cranial MRI, AIS motor and sensory scale, quality of life (spinal cord impact measurement) and modified Ashworth spasticity scale, quantitative sensory testing and neurophysiological exploration were assessed at baseline, 1, 3 and 6 months following treatment. Results Thirteen had GH deficiency. Seven received GH, five placebo and one dropped out. Both groups were similar according to clinical and demographical data at baseline, except for greater GH deficiency in the GH treatment group. At 6th month, patients treated with GH showed a significant improvement in SCIM-III score and in electrical perception threshold up to the 5th level below SCI, on both sides compared to baseline. Conclusions GHD seems to be frequent in traumatic SCI and GH replacement is safe without side effects. GH combined with physical therapy can improve quality of life of SCI patients and, strikingly, the sensory perception below lesion level.

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Association between self-esteem, depression, social support, and quality of life among patients with cerebrovascular accidents and spinal cord injury

Malaysian Journal of Movement Health & Exercise ◽

10.15282/mohe.v7i1.155 ◽

2018 ◽

Vol 7 (1) ◽

Author(s):

Adebisi Isiak Hammed ◽

Ebere Ugboh

Keyword(s):

Quality Of Life ◽

Social Support ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Short Form ◽

Self Esteem ◽

Stroke Patients ◽

Significant Difference ◽

Cord Injury

Study aim: The study determined the association between self-esteem, depression, social support and quality of life among patients with cerebrovascular accident (stroke) and spinal cord injury. Material and methods: The study adopted a cross-sectional survey research design. A total of 60 participants (30 stroke patients and 30 spinal cord injured patients) participated in this study. The selected psychosocial variables such as Depression and Self Esteem were assessed using Beck Depression Inventory Questionnaire (BDI) and Self Esteem Questionnaire (SE) respectively. Also, social support and quality of life were assessed using Social Support Questionnaire (SSQ6) and Short Form (SF-36) Health Questionnaire respectively. The association between social support, depression, self-esteem and quality of life in both spinal cord injury and stroke patients and the demographic variables were analyzed using Spearman rho. However, independent sample t-test was used to analyze the difference between social support, depression, self-esteem and quality of life in spinal cord injury and social support, depression, self-esteem and quality of life in stroke. Results: The outcome of this study showed that there is a significant difference in depression between both stroke and spinal cord injury patients (p<0.05). The findings also showed a significant association between depression, quality of life and age in stroke patients. Equally, there was a significant association between depression, social support, and age in spinal cord injury patients. Conclusion: It was therefore concluded that even though stroke patients receive more social support and have a higher quality of life, they are still more depressed and have lower self-esteem compared to spinal cord injury patients. It was thus recommended that physiotherapists and other health professionals should make an appropriate assessment of the quality of life, self-esteem, depression and social support of stroke and spinal cord injury patients to enable proper management of these individuals.

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