scholarly journals Stronger enhancer II/core promoter activities of hepatitis B virus isolates of B2 subgenotype than those of C2 subgenotype

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yanli Qin ◽  
Xueshi Zhou ◽  
Haodi Jia ◽  
Chaoyang Chen ◽  
Weifeng Zhao ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
B Virus ◽  
Enhancer Ii ◽  
Virus Isolates

scholarly journals LUC7L3/CROP inhibits replication of hepatitis B virus via suppressing enhancer II/basal core promoter activity

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yuan Li ◽  
Masahiko Ito ◽  
Suofeng Sun ◽  
Takeshi Chida ◽  
Kenji Nakashima ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Promoter Activity ◽  
Core Promoter ◽  
Basal Core Promoter ◽  
B Virus ◽  
Enhancer Ii ◽  
Core Promoter Activity

scholarly journals SREBP-1a activation by HBx and the effect on hepatitis B virus enhancer II/core promoter

2013 ◽  
Vol 432 (4) ◽  
pp. 643-649 ◽  
Author(s):  
Ling Qiao ◽  
Qi Wu ◽  
Xinya Lu ◽  
Yan Zhou ◽  
Ana Fernández-Alvarez ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
B Virus ◽  
Enhancer Ii

scholarly journals Risk for hepatocellular carcinoma with respect to hepatitis B virus genotypes B/C, specific mutations of enhancer II/core promoter/precore regions and HBV DNA levels

Gut ◽  
2007 ◽  
Vol 57 (1) ◽  
pp. 98-102 ◽  
Author(s):  
M-F Yuen ◽  
Y Tanaka ◽  
N Shinkai ◽  
R T Poon ◽  
D Y.-K. But ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
Hbv Dna ◽  
B Virus ◽  
Virus Genotypes ◽  
Enhancer Ii

Specific mutations in the enhancer II/core promoter/precore regions of hepatitis B virus subgenotype C2 in Korean patients with hepatocellular carcinoma

2009 ◽  
Vol 81 (6) ◽  
pp. 1002-1008 ◽  
Author(s):  
Ja Kyung Kim ◽  
Hye Young Chang ◽  
Jung Min Lee ◽  
Oidov Baatarkhuu ◽  
Young Joon Yoon ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
Korean Patients ◽  
B Virus ◽  
Enhancer Ii

scholarly journals A Quasi Species of the pre‐S/S Gene and Mutations of Enhancer II/Core Promoter/pre‐C in Mothers and Their Children Infected with Hepatitis B Virus via Mother‐to‐Infant Transmission

2006 ◽  
Vol 193 (1) ◽  
pp. 88-97 ◽  
Author(s):  
Hongmei Xu ◽  
Mingli Peng ◽  
Yuling Qing ◽  
Ning Ling ◽  
Yinghua Lan ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
S Gene ◽  
B Virus ◽  
Enhancer Ii

scholarly journals Novel point mutations and mutational complexes in the enhancer II, core promoter and precore regions of hepatitis B virus genotype D1 associated with hepatocellular carcinoma in Saudi Arabia

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Anis Khan ◽  
Mohammed A. Al Balwi ◽  
Yasuhito Tanaka ◽  
Ali Hajeer ◽  
Faisal M. Sanai ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Saudi Arabia ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
Point Mutations ◽  
Virus Genotype ◽  
B Virus ◽  
Enhancer Ii

scholarly journals A study on sequence variations in pre-S/surface, X and enhancer II/core promoter/precore regions of occult hepatitis B virus in non-B, non-C hepatocellular carcinoma patients in Taiwan

2009 ◽  
Vol 125 (3) ◽  
pp. 621-629 ◽  
Author(s):  
Chien-Hung Chen ◽  
Chi-Sin Changchien ◽  
Chuan-Mo Lee ◽  
Wei-Chih Tung ◽  
Chao-Hung Hung ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
Occult Hepatitis ◽  
Sequence Variations ◽  
B Virus ◽  
Occult Hepatitis B ◽  
Enhancer Ii

Mutations in the Core Promoter/Enhancer II Regions of Naturally Occurring Hepatitis B Virus Variants and Analysis of the Effects on Transcription Activities

Intervirology ◽  
1995 ◽  
Vol 38 (5) ◽  
pp. 290-294 ◽  
Author(s):  
Akira Nishizono ◽  
Masaharu Hiraga ◽  
Kazuhiro Kohno ◽  
Yoshiko T. Sonoda ◽  
Hideo Terao ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
The Core ◽  
Naturally Occurring ◽  
B Virus ◽  
Enhancer Ii

scholarly journals Site-specific mutation of the hepatitis B virus enhancer II B1 element: effect on virus transcription and replication

2001 ◽  
Vol 82 (3) ◽  
pp. 531-535 ◽  
Author(s):  
Youhua Xie ◽  
Mei Li ◽  
Yuan Wang ◽  
Peter Hans Hofschneider ◽  
Ludwig Weiss
Keyword(s):  
Hepatitis B Virus ◽  
Dna Replication ◽  
Hepatitis B ◽  
Binding Site ◽  
Mutational Analysis ◽  
Core Promoter ◽  
Viral Gene ◽  
Single Point Mutation ◽  
B Virus ◽  
Enhancer Ii

The hepatitis B virus (HBV) enhancer II (EII) is highly liver-specific and plays an important role in regulating the transcription of all HBV genes. In this report, mutational analysis on the B1F-binding site in the major functional unit of HBV EII is described. The activity of HBV EII in EII–CAT reporter plasmids was significantly decreased when the sequence of the B1F-binding site in EII was mutated. Furthermore, a single point mutation in the B1 element that aborted the binding of B1F caused a dramatic decrease in viral gene transcription initiated from the HBV core promoter, which resulted in a reduction of the production of the HBV e antigen and pregenomic RNA, the template for viral DNA replication. In conclusion, the interaction of B1F with its target binding sequence in the EII region is crucial for liver-specific transcription and DNA replication of the virus.

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