scholarly journals Molecular basis for the behavioral effects of the odorant degrading enzyme Esterase 6 in Drosophila

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Faisal Younus ◽  
Nicholas J. Fraser ◽  
Chris W. Coppin ◽  
Jian-Wei Liu ◽  
Galen J. Correy ◽  
...  
Keyword(s):  
Molecular Basis ◽  
Behavioral Effects ◽  
Degrading Enzyme ◽  
Esterase 6

scholarly journals Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-α, and Amylin by Human Insulin-Degrading Enzyme

2010 ◽  
Vol 395 (2) ◽  
pp. 430-443 ◽  
Author(s):  
Qing Guo ◽  
Marika Manolopoulou ◽  
Yao Bian ◽  
Alexander B. Schilling ◽  
Wei-Jen Tang
Keyword(s):  
Human Insulin ◽  
Molecular Basis ◽  
Insulin Degrading Enzyme ◽  
Degrading Enzyme

scholarly journals Molecular Basis of Catalytic Chamber-assisted Unfolding and Cleavage of Human Insulin by Human Insulin-degrading Enzyme

2009 ◽  
Vol 284 (21) ◽  
pp. 14177-14188 ◽  
Author(s):  
Marika Manolopoulou ◽  
Qing Guo ◽  
Enrico Malito ◽  
Alexander B. Schilling ◽  
Wei-Jen Tang
Keyword(s):  
Human Insulin ◽  
Molecular Basis ◽  
Insulin Degrading Enzyme ◽  
Degrading Enzyme

scholarly journals Molecular basis for the thiol sensitivity of insulin-degrading enzyme

2008 ◽  
Vol 105 (28) ◽  
pp. 9582-9587 ◽  
Author(s):  
M. Neant-Fery ◽  
R. D. Garcia-Ordonez ◽  
T. P. Logan ◽  
D. J. Selkoe ◽  
L. Li ◽  
...  
Keyword(s):  
Molecular Basis ◽  
Insulin Degrading Enzyme ◽  
Degrading Enzyme

scholarly journals An antennal carboxylesterase from Drosophila melanogaster, esterase 6, is a candidate odorant-degrading enzyme toward food odorants

2015 ◽  
Vol 6 ◽  
Author(s):  
Thomas Chertemps ◽  
Faisal Younus ◽  
Claudia Steiner ◽  
Nicolas Durand ◽  
Chris W. Coppin ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Degrading Enzyme ◽  
Esterase 6

Site directed mutagenesis of insulin-degrading enzyme allows singling out the molecular basis of peptidase versus E1-like activity: the role of metal ions

Metallomics ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 278-281 ◽  
Author(s):  
Francesco Bellia ◽  
Valeria Lanza ◽  
Ikhlas Mohamed Mohamud Ahmed ◽  
Sara Garcia-Vinuales ◽  
Eva Veiss ◽  
...  
Keyword(s):  
Metal Ions ◽  
Molecular Basis ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis ◽  
Insulin Degrading Enzyme ◽  
Degrading Enzyme

Four specifically designed IDE mutants have been used to unveil the molecular basis of peptidase versus E1-like activity of the enzyme.

Renilla Bioluminescence: A Morphologic Approach to the Location of Photocytes

1974 ◽  
Vol 32 ◽  
pp. 208-209
Author(s):  
Ben O. Spurlock ◽  
Milton J. Cormier
Keyword(s):  
Excited State ◽  
Ground State ◽  
Molecular Basis ◽  
Light Emission ◽  
Chemical Basis ◽  
Electronic Excited State ◽  
Colonial Form ◽  
The Common ◽  
Eighteenth And Nineteenth Centuries ◽  
Catalyzed Oxidation

The phenomenon of bioluminescence has fascinated layman and scientist alike for many centuries. During the eighteenth and nineteenth centuries a number of observations were reported on the physiology of bioluminescence in Renilla, the common sea pansy. More recently biochemists have directed their attention to the molecular basis of luminosity in this colonial form. These studies have centered primarily on defining the chemical basis for bioluminescence and its control. It is now established that bioluminescence in Renilla arises due to the luciferase-catalyzed oxidation of luciferin. This results in the creation of a product (oxyluciferin) in an electronic excited state. The transition of oxyluciferin from its excited state to the ground state leads to light emission.

Androgen-induced plasticity at a “vocal” neuromuscular synapse

1994 ◽  
Vol 52 ◽  
pp. 32-33
Author(s):  
Darcy B. Kelley ◽  
Martha L. Tobias ◽  
Mark Ellisman
Keyword(s):  
Xenopus Laevis ◽  
Motor Neurons ◽  
Sexual Differentiation ◽  
Molecular Basis ◽  
Neuromuscular Synapse ◽  
Sexually Dimorphic ◽  
Intracellular Protein ◽  
Developmental Program ◽  
Androgen Action ◽  
Clawed Frog

Brain and muscle are sexually differentiated tissues in which masculinization is controlled by the secretion of androgens from the testes. Sensitivity to androgen is conferred by the expression of an intracellular protein, the androgen receptor. A central problem of sexual differentiation is thus to understand the cellular and molecular basis of androgen action. We do not understand how hormone occupancy of a receptor translates into an alteration in the developmental program of the target cell. Our studies on sexual differentiation of brain and muscle in Xenopus laevis are designed to explore the molecular basis of androgen induced sexual differentiation by examining how this hormone controls the masculinization of brain and muscle targets.Our approach to this problem has focused on a highly androgen sensitive, sexually dimorphic neuromuscular system: laryngeal muscles and motor neurons of the clawed frog, Xenopus laevis. We have been studying sex differences at a synapse, the laryngeal neuromuscular junction, which mediates sexually dimorphic vocal behavior in Xenopus laevis frogs.

A molecular basis for opiate action

1998 ◽  
Vol 33 ◽  
pp. 65-77 ◽  
Author(s):  
Dominique Massotte ◽  
Brigitte L. Kieffer
Keyword(s):  
Molecular Basis

Treatment of severe endometriosis with an aromatase inhibitor: A novel indication and its molecular basis

1998 ◽  
Vol 5 (1) ◽  
pp. 96A-96A ◽  
Author(s):  
K ZEITOUN ◽  
K TAKAYAMA ◽  
R GUNBY ◽  
B CARR ◽  
S BULUN
Keyword(s):  
Aromatase Inhibitor ◽  
Molecular Basis
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