Targeting synthetic analogues of the metallo-sulfur active sites of nickel enzymes capable of important catalysis

2003 ◽  
pp. 4147-4151 ◽  
Author(s):  
Matt C. Smith ◽  
J. Elaine Barclay ◽  
Sian C. Davies ◽  
David L. Hughes ◽  
David J. Evans
Keyword(s):  
Active Sites ◽  
Synthetic Analogues ◽  
Nickel Enzymes

scholarly journals Synthetic Analogues of the Active Sites of Nitrogenase and [NiFe] Hydrogenase

2014 ◽  
Vol 87 (1) ◽  
pp. 1-19 ◽  
Author(s):  
Yasuhiro Ohki
Keyword(s):  
Active Sites ◽  
Synthetic Analogues

ChemInform Abstract: Synthetic Analogues of the Active Sites of Nitrogenase and [NiFe] Hydrogenase

ChemInform ◽  
2014 ◽  
Vol 45 (12) ◽  
pp. no-no
Author(s):  
Yasuhiro Ohki
Keyword(s):  
Active Sites ◽  
Synthetic Analogues

Synthetic Analogues of the Active Sites of Iron-Sulfur Proteins

1993 ◽  
pp. 278-295 ◽  
Author(s):  
Guillermo González-Moraga
Keyword(s):  
Active Sites ◽  
Synthetic Analogues ◽  
Iron Sulfur ◽  
Iron Sulfur Proteins

Synthetic Analogues of the Active Sites of Iron—Sulfur Proteins

ChemInform ◽  
2004 ◽  
Vol 35 (21) ◽  
Author(s):  
P. Venkateswara Rao ◽  
R. H. Holm
Keyword(s):  
Active Sites ◽  
Synthetic Analogues ◽  
Iron Sulfur ◽  
Iron Sulfur Proteins

Controlling O2 Reactivity in Synthetic Analogues of [NiFeS]- and [NiFeSe]-Hydrogenase Active Sites

2019 ◽  
Vol 141 (38) ◽  
pp. 15338-15347 ◽  
Author(s):  
Xuemei Yang ◽  
Lindy C. Elrod ◽  
Trung Le ◽  
Valeria S. Vega ◽  
Haley Naumann ◽  
...  
Keyword(s):  
Active Sites ◽  
Synthetic Analogues

Synthetic Analogues of the Active Sites of Iron−Sulfur Proteins

2004 ◽  
Vol 104 (2) ◽  
pp. 527-560 ◽  
Author(s):  
P. Venkateswara Rao ◽  
R. H. Holm
Keyword(s):  
Active Sites ◽  
Synthetic Analogues ◽  
Iron Sulfur ◽  
Iron Sulfur Proteins

What catalysis needs from the electron microscopist

1988 ◽  
Vol 46 ◽  
pp. 694-695
Author(s):  
Alexis T. Bell
Keyword(s):  
Active Sites ◽  
Heterogeneous Catalysts ◽  
Catalyst Deactivation ◽  
Surface Composition ◽  
Internal Surface ◽  
Active Phase ◽  
Atomic Scale ◽  
Metal Catalyst ◽  
Internal Surface Area ◽  
Porous Support

Heterogeneous catalysts, used in industry for the production of fuels and chemicals, are microporous solids characterized by a high internal surface area. The catalyticly active sites may occur at the surface of the bulk solid or of small crystallites deposited on a porous support. An example of the former case would be a zeolite, and of the latter, a supported metal catalyst. Since the activity and selectivity of a catalyst are known to be a function of surface composition and structure, it is highly desirable to characterize catalyst surfaces with atomic scale resolution. Where the active phase is dispersed on a support, it is also important to know the dispersion of the deposited phase, as well as its structural and compositional uniformity, the latter characteristics being particularly important in the case of multicomponent catalysts. Knowledge of the pore size and shape is also important, since these can influence the transport of reactants and products through a catalyst and the dynamics of catalyst deactivation.

Scanning luminescence x-ray microscopy: Progress toward selective staining using microspheres

1994 ◽  
Vol 52 ◽  
pp. 74-75
Author(s):  
C. Jacobsen ◽  
J. Fu ◽  
S. Mayer ◽  
Y. Wang ◽  
S. Williams
Keyword(s):  
Visible Light ◽  
Active Sites ◽  
Light Emission ◽  
Chinese Hamster ◽  
Polystyrene Spheres ◽  
Good Resistance ◽  
X Ray ◽  
Selective Staining ◽  
Visible Light Emission ◽  
Specific Labelling

In scanning luminescence x-ray microscopy (SLXM), a high resolution x-ray probe is used to excite visible light emission (see Figs. 1 and 2). The technique has been developed with a goal of localizing dye-tagged biochemically active sites and structures at 50 nm resolution in thick, hydrated biological specimens. Following our initial efforts, Moronne et al. have begun to develop probes based on biotinylated terbium; we report here our progress towards using microspheres for tagging.Our initial experiments with microspheres were based on commercially-available carboxyl latex spheres which emitted ~ 5 visible light photons per x-ray absorbed, and which showed good resistance to bleaching under x-ray irradiation. Other work (such as that by Guo et al.) has shown that such spheres can be used for a variety of specific labelling applications. Our first efforts have been aimed at labelling ƒ actin in Chinese hamster ovarian (CHO) cells. By using a detergent/fixative protocol to load spheres into cells with permeabilized membranes and preserved morphology, we have succeeded in using commercial dye-loaded, spreptavidin-coated 0.03μm polystyrene spheres linked to biotin phalloidon to label f actin (see Fig. 3).

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