Electrochemical impedance spectroscopy and surface plasmon resonance studies of DNA hybridization on gold/SiOx interfaces

The Analyst ◽  
2008 ◽  
Vol 133 (8) ◽  
pp. 1097 ◽  
Author(s):  
Maël Manesse ◽  
Valerie Stambouli ◽  
Rabah Boukherroub ◽  
Sabine Szunerits
2007 ◽  
Vol 79 (13) ◽  
pp. 4879-4886 ◽  
Author(s):  
Rita Maalouf ◽  
Chantal Fournier-Wirth ◽  
Joliette Coste ◽  
Hanna Chebib ◽  
Youssef Saïkali ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Garima Dobhal ◽  
Amrita Datta ◽  
Deanna Ayupova ◽  
Paul Teesdale-Spittle ◽  
Renee V. Goreham

Abstract The physical characterisation, capture and detection of extracellular vesicles (EVs) and exosomes derived from breath condensate is reported. Breath-derived EVs were isolated from breath condensate and captured on a gold substrate using two complimentary methods. The characterised and isolated EVs were detected using surface plasmon resonance (SPR) and electrochemical impedance spectroscopy (EIS). EIS was done using aptamers as a targeting moiety and showed a larger change in resistance between dilute concentrations of EVs (less than 7 μg/mL).This is the first report of EVs and exosomes isolated and characterised from breath. In addition, EVs from a non-invasive and easily available source such as breath opens up further avenues in the detection of pulmonary diseases.


Sign in / Sign up

Export Citation Format

Share Document