Integrated biosensor for simultaneous detection by surface plasmon resonance and Faradaic electrochemical impedance spectroscopy

2016 ◽  
Author(s):  
Brandon Hong ◽  
Alexander Sun ◽  
Lin Pang ◽  
A.G. Venkatesh ◽  
Drew Hall ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Electrochemical Impedance Spectroscopy ◽  
Impedance Spectroscopy ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Electrochemical Impedance ◽  
Simultaneous Detection

Label-Free Detection of Bacteria by Electrochemical Impedance Spectroscopy:  Comparison to Surface Plasmon Resonance

2007 ◽  
Vol 79 (13) ◽  
pp. 4879-4886 ◽  
Author(s):  
Rita Maalouf ◽  
Chantal Fournier-Wirth ◽  
Joliette Coste ◽  
Hanna Chebib ◽  
Youssef Saïkali ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Electrochemical Impedance Spectroscopy ◽  
Impedance Spectroscopy ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Electrochemical Impedance ◽  
Label Free ◽  
Label Free Detection

scholarly journals Isolation, characterisation and detection of breath-derived extracellular vesicles

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Garima Dobhal ◽  
Amrita Datta ◽  
Deanna Ayupova ◽  
Paul Teesdale-Spittle ◽  
Renee V. Goreham
Keyword(s):  
Surface Plasmon Resonance ◽  
Electrochemical Impedance Spectroscopy ◽  
Impedance Spectroscopy ◽  
Extracellular Vesicles ◽  
Surface Plasmon ◽  
Electrochemical Impedance ◽  
Pulmonary Diseases ◽  
Gold Substrate ◽  
Non Invasive ◽  
Breath Condensate

Abstract The physical characterisation, capture and detection of extracellular vesicles (EVs) and exosomes derived from breath condensate is reported. Breath-derived EVs were isolated from breath condensate and captured on a gold substrate using two complimentary methods. The characterised and isolated EVs were detected using surface plasmon resonance (SPR) and electrochemical impedance spectroscopy (EIS). EIS was done using aptamers as a targeting moiety and showed a larger change in resistance between dilute concentrations of EVs (less than 7 μg/mL).This is the first report of EVs and exosomes isolated and characterised from breath. In addition, EVs from a non-invasive and easily available source such as breath opens up further avenues in the detection of pulmonary diseases.

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