Label-free electrochemiluminescent immunosensor for α-fetoprotein: performance of Nafion–carbon nanodots nanocomposite films as antibody carriers

2012 ◽  
Vol 48 (25) ◽  
pp. 3055-3057 ◽  
Author(s):  
Hong Dai ◽  
Caiping Yang ◽  
Yuejin Tong ◽  
Guifang Xu ◽  
Xiuling Ma ◽  
...  
2020 ◽  
Vol 8 (23) ◽  
pp. 5089-5095
Author(s):  
Fangfang Du ◽  
Zhe Cheng ◽  
Marius Kremer ◽  
Yang Liu ◽  
Xiaodong Wang ◽  
...  

Illustration of the synthetic procedure of N-CNDs and N-CDs-based bifunctional fluorescence nanoprobe for the detection of VB12 and Co2+ and bioimaging of A549 cell and zebrafish.


2015 ◽  
Vol 7 (10) ◽  
pp. 4038-4043 ◽  
Author(s):  
Buhong Gao ◽  
Ying Tang ◽  
Haijun Sun ◽  
Yan Xuan ◽  
Li Xu ◽  
...  

Based on the principle of fluorescence recovery, we propose a simple label-free and turn-on method for the detection of I− ions with high selectivity and sensitivity by using fluorescent Cdots/Ag nanocomposites in aqueous media.


2015 ◽  
Vol 3 (37) ◽  
pp. 19018-19026 ◽  
Author(s):  
Kisu Lee ◽  
Sunghun Cho ◽  
Minkyu Kim ◽  
Jihoo Kim ◽  
Jaehoon Ryu ◽  
...  

A novel method to synthesize highly porous polyaniline (PANI) using carbon nanodots (CNDs) is reported. PANI-CND nanocomposite films exhibited high electrical conductivity (774 S cm−1) and excellent performance as counter electrodes in dye-sensitized solar cells (η = 7.45%).


2012 ◽  
Vol 48 (8) ◽  
pp. 1147-1149 ◽  
Author(s):  
Li Zhou ◽  
Youhui Lin ◽  
Zhenzhen Huang ◽  
Jinsong Ren ◽  
Xiaogang Qu

2020 ◽  
Vol 412 (12) ◽  
pp. 2893-2901 ◽  
Author(s):  
Jingqi Chen ◽  
Xiaowei Liu ◽  
Xialing Hou ◽  
Yingying Chen ◽  
Feifei Xing ◽  
...  

2013 ◽  
Vol 47 ◽  
pp. 133-140 ◽  
Author(s):  
S. Radhakrishnan ◽  
C. Sumathi ◽  
Ahmad Umar ◽  
Sang Jae Kim ◽  
J. Wilson ◽  
...  

2020 ◽  
Author(s):  
Nikolas Hundt

Abstract Single-molecule imaging has mostly been restricted to the use of fluorescence labelling as a contrast mechanism due to its superior ability to visualise molecules of interest on top of an overwhelming background of other molecules. Recently, interferometric scattering (iSCAT) microscopy has demonstrated the detection and imaging of single biomolecules based on light scattering without the need for fluorescent labels. Significant improvements in measurement sensitivity combined with a dependence of scattering signal on object size have led to the development of mass photometry, a technique that measures the mass of individual molecules and thereby determines mass distributions of biomolecule samples in solution. The experimental simplicity of mass photometry makes it a powerful tool to analyse biomolecular equilibria quantitatively with low sample consumption within minutes. When used for label-free imaging of reconstituted or cellular systems, the strict size-dependence of the iSCAT signal enables quantitative measurements of processes at size scales reaching from single-molecule observations during complex assembly up to mesoscopic dynamics of cellular components and extracellular protrusions. In this review, I would like to introduce the principles of this emerging imaging technology and discuss examples that show how mass-sensitive iSCAT can be used as a strong complement to other routine techniques in biochemistry.


2003 ◽  
Vol 773 ◽  
Author(s):  
Myung-Il Park ◽  
Jonging Hong ◽  
Dae Sung Yoon ◽  
Chong-Ook Park ◽  
Geunbae Im

AbstractThe large optical detection systems that are typically utilized at present may not be able to reach their full potential as portable analysis tools. Accurate, early, and fast diagnosis for many diseases requires the direct detection of biomolecules such as DNA, proteins, and cells. In this research, a glass microchip with integrated microelectrodes has been fabricated, and the performance of electrochemical impedance detection was investigated for the biomolecules. We have used label-free λ-DNA as a sample biomolecule. By changing the distance between microelectrodes, the significant difference between DW and the TE buffer solution is obtained from the impedance-frequency measurements. In addition, the comparison for the impedance magnitude of DW, the TE buffer, and λ-DNA at the same distance was analyzed.


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