Fluorescent and paramagnetic core–shell hybrid nanoparticles for bi-modal magnetic resonance/luminescence imaging

2012 ◽  
Vol 22 (38) ◽  
pp. 20641 ◽  
Author(s):  
Weihua Di ◽  
Sabareesh K. P. Velu ◽  
Alessandro Lascialfari ◽  
Chunxu Liu ◽  
Nicola Pinna ◽  
...  
ACS Omega ◽  
2021 ◽  
Author(s):  
Uliana Kostiv ◽  
Marta Maria Natile ◽  
Daniel Jirák ◽  
Denisa Půlpánová ◽  
Klára Jiráková ◽  
...  

2017 ◽  
Vol 14 (3) ◽  
pp. 342-348 ◽  
Author(s):  
Yuanwen Zou ◽  
Zhi Wu ◽  
Zhongbing Huang ◽  
Guangfu Yin ◽  
Lei Wang ◽  
...  

2021 ◽  
Vol 20 ◽  
pp. 153303382110365
Author(s):  
Lin Qiu ◽  
Shuwen Zhou ◽  
Ying Li ◽  
Wen Rui ◽  
Pengfei Cui ◽  
...  

Bifunctional magnetic/fluorescent core-shell silica nanospheres (MNPs) encapsulated with the magnetic Fe3O4 core and a derivate of 8-amimoquinoline (N-(quinolin-8-yl)-2-(3-(triethoxysilyl) propylamino) acetamide) (QTEPA) into the shell were synthesized. These functional MNPs were prepared with a modified stöber method and the formed Fe3O4@SiO2-QTEPA core-shell nanocomposites are biocompatible, water-dispersible, and stable. These prepared nanoparticles were characterized by X-ray power diffraction (XRD), transmission electron microscopy (TEM), thermoelectric plasma Quad II inductively coupled plasma mass spectrometry (ICP-MS), superconducting quantum interference device (SQUID), TG/DTA thermal analyzer (TGA) and Fourier transform infrared spectroscopy (FTIR). Further application of the nanoparticles in detecting Zn2+ was confirmed by the fluorescence experiment: the nanosensor shows high selectivity and sensitivity to Zn2+ with a 22-fold fluorescence emission enhancement in the presence of 10 μM Zn2+. Moreover, the transverse relaxivity measurements show that the core-shell MNPs have T2 relaxivity (r2) of 155.05 mM−1 S−1 based on Fe concentration on the 3.0 T scanner, suggesting that the compound can be used as a negative contrast agent for MRI. Further in vivo experiments showed that these MNPs could be used as MRI contrast agent. Therefore, the new nanosensor provides the dual modality of magnetic resonance imaging and optical imaging.


RSC Advances ◽  
2018 ◽  
Vol 8 (47) ◽  
pp. 26764-26770 ◽  
Author(s):  
Kaili Wang ◽  
Lu An ◽  
Qiwei Tian ◽  
Jiaomin Lin ◽  
Shiping Yang

Magnetic resonance imaging (MRI) is indispensable and powerful in modern clinical diagnosis and has some advantages such as non-invasiveness and high penetration depth.


RSC Advances ◽  
2016 ◽  
Vol 6 (23) ◽  
pp. 18843-18851 ◽  
Author(s):  
N. Venkatesha ◽  
Yasrib Qurishi ◽  
Hanudatta S. Atreya ◽  
Chandan Srivastava

The potential of CoFe2O4–ZnO core–shell nanoparticles for fluorescence optical imaging and as a contrast agent for magnetic resonance imaging (MRI) is demonstrated.


2018 ◽  
Vol 8 (3) ◽  
pp. 411 ◽  
Author(s):  
Mehrdad Khatami ◽  
Hajar Alijani ◽  
Meysam Nejad ◽  
Rajender Varma

Among an array of hybrid nanoparticles, core-shell nanoparticles comprise of two or more materials, such as metals and biomolecules, wherein one of them forms the core at the center, while the other material/materials that were located around the central core develops a shell. Core-shell nanostructures are useful entities with high thermal and chemical stability, lower toxicity, greater solubility, and higher permeability to specific target cells. Plant or natural products-mediated synthesis of nanostructures refers to the use of plants or its extracts for the synthesis of nanostructures, an emerging field of sustainable nanotechnology. Various physiochemical and greener methods have been advanced for the synthesis of nanostructures, in contrast to conventional approaches that require the use of synthetic compounds for the assembly of nanostructures. Although several biological resources have been exploited for the synthesis of core-shell nanoparticles, but plant-based materials appear to be the ideal candidates for large-scale green synthesis of core-shell nanoparticles. This review summarizes the known strategies for the greener production of core-shell nanoparticles using plants extract or their derivatives and highlights their salient attributes, such as low costs, the lack of dependence on the use of any toxic materials, and the environmental friendliness for the sustainable assembly of stabile nanostructures.


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