This paper deals with two topics concerning two-dimensional automata operating in parallel. We first investigate a relationship between the accepting powers of two-dimensional alternating finite automata (2-AFAs) and nondeterministic bottom-up pyramid cellular acceptors (NUPCAs), and show that Ω ( diameter × log diameter ) time is necessary for NUPCAs to simulate 2-AFAs. We then investigate space complexity of two-dimensional alternating Turing machines (2-ATMs) operating in small space, and show that if L (n) is a two-dimensionally space-constructible function such that lim n → ∞ L (n)/ loglog n > 1 and L (n) ≤ log n, and L′ (n) is a function satisfying L′ (n) =o (L(n)), then there exists a set accepted by some strongly L (n) space-bounded two-dimensional deterministic Turing machine, but not accepted by any weakly L′ (n) space-bounded 2-ATM, and thus there exists a rich space hierarchy for weakly S (n) space-bounded 2-ATMs with loglog n ≤ S (n) ≤ log n.
Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor
