Highly efficient single-cell analysis of microbial cells by time-resolved inductively coupled plasma mass spectrometry

2014 ◽  
Vol 29 (9) ◽  
pp. 1598-1606 ◽  
Author(s):  
Shin-ichi Miyashita ◽  
Alexander S. Groombridge ◽  
Shin-ichiro Fujii ◽  
Ayumi Minoda ◽  
Akiko Takatsu ◽  
...  
Keyword(s):  
Single Cell ◽  
Inductively Coupled Plasma ◽  
Single Cell Analysis ◽  
High Time Resolution ◽  
Time Resolved ◽  
Microbial Cells ◽  
Inductively Coupled ◽  
Highly Efficient ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

Highly efficient single-cell elemental analysis of microbial cells was achieved using a developed ICP-MS system with approximately 100% cell introduction efficiency and high time resolution.

Single-cell analysis by use of ICP-MS

2020 ◽  
Vol 35 (9) ◽  
pp. 1784-1813 ◽  
Author(s):  
Sarah Theiner ◽  
Konrad Loehr ◽  
Gunda Koellensperger ◽  
Larissa Mueller ◽  
Norbert Jakubowski
Keyword(s):  
Mass Spectrometry ◽  
Single Cell ◽  
Inductively Coupled Plasma ◽  
Single Cell Analysis ◽  
Review Article ◽  
Cell Analysis ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Recent Trends

This tutorial review article is highlighting the fundamentals, instrumentation, and most recent trends of single-cell analysis by use of inductively coupled plasma-mass spectrometry (ICP-MS).

An interactive Python-based data processing platform for single particle and single cell ICP-MS

2021 ◽  
Author(s):  
Thomas Edward Lockwood ◽  
Raquel Gonzalez de Vega ◽  
David Clases
Keyword(s):  
Mass Spectrometry ◽  
Data Processing ◽  
Single Cell ◽  
Single Particle ◽  
Inductively Coupled Plasma ◽  
Medical Sciences ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Processing Platform

Single particle (SP) and single cell (SC) inductively coupled plasma-mass spectrometry (ICP-MS) are gaining increas-ing momentum in environmental and medical sciences for the analysis of nanoparticles, microstructures, and individ-ual cells....

Single Particle Inductively Coupled Plasma Mass Spectrometry: Investigating Nonlinear Response Observed in Pulse Counting Mode and Extending the Linear Dynamic Range by Compensating for Dead Time Related Count Losses on a Microsecond Timescale

2019 ◽  
Author(s):  
Ingo Strenge ◽  
Carsten Engelhard
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Nonlinear Response ◽  
Dynamic Range ◽  
Dead Time ◽  
Inorganic Nanoparticles ◽  
Linear Dynamic Range ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

<p>The article demonstrates the importance of using a suitable approach to compensate for dead time relate count losses (a certain measurement artefact) whenever short, but potentially strong transient signals are to be analysed using inductively coupled plasma mass spectrometry (ICP-MS). Findings strongly support the theory that inadequate time resolution, and therefore insufficient compensation for these count losses, is one of the main reasons for size underestimation observed when analysing inorganic nanoparticles using ICP-MS, a topic still controversially discussed.</p>

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