scholarly journals Vesicular disruption of lysosomal targeting organometallic polyarginine bioconjugates

Metallomics ◽  
2015 ◽  
Vol 7 (2) ◽  
pp. 371-384 ◽  
Author(s):  
Annika Gross ◽  
Hamed Alborzinia ◽  
Stefania Piantavigna ◽  
Lisandra L. Martin ◽  
Stefan Wölfl ◽  
...  
Keyword(s):  
Biological Activity ◽  
Cancer Therapy ◽  
Membrane Permeabilization ◽  
Lysosomal Membrane ◽  
Lysosomal Membrane Permeabilization ◽  
Cell Penetrating ◽  
A Cell ◽  
Lysosomal Targeting ◽  
Derivatives Of ◽  
Metallocene Derivatives

Targeting of lysosomes is an interesting, novel pathway for cancer therapy. in this work, novel metallocene derivatives (of ferrocene and ruthenocene) of a cell penetrating polyarginine peptide are presented as lysosomal membrane permeabilization (LMP) agents and their localization and biological activity is investigated in detail.

A novel tool for detecting lysosomal membrane permeabilization by high-throughput fluorescence microscopy

2020 ◽  
Author(s):  
Karla Alvarez-Valadez ◽  
Allan Sauvat ◽  
Hélène Fohrer-Ting ◽  
Christophe Klein ◽  
Oliver Kepp ◽  
...  
Keyword(s):  
Fluorescence Microscopy ◽  
High Throughput ◽  
Membrane Permeabilization ◽  
Lysosomal Membrane ◽  
Lysosomal Membrane Permeabilization

scholarly journals Lipotoxicity-mediated cell dysfunction and death involve lysosomal membrane permeabilization and cathepsin L activity

2010 ◽  
Vol 1318 ◽  
pp. 133-143 ◽  
Author(s):  
Frankis G. Almaguel ◽  
Jo-Wen Liu ◽  
Fabio J. Pacheco ◽  
Daisy De Leon ◽  
Carlos A. Casiano ◽  
...  
Keyword(s):  
Cathepsin L ◽  
Membrane Permeabilization ◽  
Lysosomal Membrane ◽  
Lysosomal Membrane Permeabilization ◽  
Cell Dysfunction

Visualizing Lysosomal Membrane Permeabilization by Fluorescent Dextran Release: Figure 1.

2015 ◽  
Vol 2015 (10) ◽  
pp. pdb.prot086173 ◽  
Author(s):  
Anne-Marie Ellegaard ◽  
Marja Jäättelä ◽  
Jesper Nylandsted
Keyword(s):  
Membrane Permeabilization ◽  
Lysosomal Membrane ◽  
Lysosomal Membrane Permeabilization ◽  
Fluorescent Dextran

Enniatin B1-induced lysosomal membrane permeabilization in mouse embryonic fibroblasts

2019 ◽  
Vol 36 (1) ◽  
pp. 23-30 ◽  
Author(s):  
Carlos A. F. Oliveira ◽  
Lada Ivanova ◽  
Anita Solhaug ◽  
Christiane K. Fæste
Keyword(s):  
Membrane Permeabilization ◽  
Lysosomal Membrane ◽  
Mouse Embryonic Fibroblasts ◽  
Embryonic Fibroblasts ◽  
Lysosomal Membrane Permeabilization
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