scholarly journals Molecular release from patterned nanoporous gold thin films

Nanoscale ◽  
2014 ◽  
Vol 6 (12) ◽  
pp. 7062-7071 ◽  
Author(s):  
Ozge Kurtulus ◽  
Pallavi Daggumati ◽  
Erkin Seker
Keyword(s):  
Thin Films ◽  
Small Molecules ◽  
Release Kinetics ◽  
Nanoporous Gold ◽  
High Loading ◽  
Loading Capacity ◽  
Tunable Release ◽  
Gold Thin Films

Patterned nanoporous gold thin films exhibit high loading capacity and tunable release kinetics for small molecules.

scholarly journals A Microfluidic Platform to Study Astrocyte Adhesion on Nanoporous Gold Thin Films

Nanomaterials ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. 452 ◽  
Author(s):  
Alexander Hampe ◽  
Zidong Li ◽  
Sunjay Sethi ◽  
Pamela Lein ◽  
Erkin Seker
Keyword(s):  
Thin Films ◽  
Nanoporous Gold ◽  
Microfluidic Platform ◽  
Gold Thin Films

Fabrication of nanoporous gold thin films on glass substrates for amperometric sensing of aniline

2017 ◽  
Vol 713 ◽  
pp. 132-137 ◽  
Author(s):  
Keon-U Lee ◽  
Trung Hieu Tran ◽  
Sang Hoon Kim ◽  
Hyung-Joon Shin
Keyword(s):  
Thin Films ◽  
Nanoporous Gold ◽  
Glass Substrates ◽  
Amperometric Sensing ◽  
Gold Thin Films

scholarly journals Electrochemically Triggered Pore Expansion in Nanoporous Gold Thin Films

2016 ◽  
Vol 120 (7) ◽  
pp. 4080-4086 ◽  
Author(s):  
Tatiana S. Dorofeeva ◽  
Zimple Matharu ◽  
Pallavi Daggumati ◽  
Erkin Seker
Keyword(s):  
Thin Films ◽  
Nanoporous Gold ◽  
Gold Thin Films ◽  
Pore Expansion

scholarly journals Engineering on-chip nanoporous gold material libraries via precision photothermal treatment

Nanoscale ◽  
2016 ◽  
Vol 8 (2) ◽  
pp. 785-795 ◽  
Author(s):  
Christopher A. R. Chapman ◽  
Ling Wang ◽  
Juergen Biener ◽  
Erkin Seker ◽  
Monika M. Biener ◽  
...  
Keyword(s):  
Thin Films ◽  
Nanoporous Gold ◽  
Parallel Structure ◽  
Structure Property ◽  
Property Relationship ◽  
Photothermal Treatment ◽  
Structure Property Relationship ◽  
Gold Thin Films ◽  
On Chip

Photothermal treatment of nanoporous gold thin films enables fabrication of patterned on-chip material libraries for use in parallel structure–property relationship studies.

scholarly journals Nanoporous Gold Monolith for High Loading of Unmodified Doxorubicin and Sustained Co-Release of Doxorubicin-Rapamycin

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 208 ◽  
Author(s):  
Jay K. Bhattarai ◽  
Dharmendra Neupane ◽  
Bishal Nepal ◽  
Alexei V. Demchenko ◽  
Keith J. Stine
Keyword(s):  
Release Kinetics ◽  
Protein Corona ◽  
Nanoporous Gold ◽  
High Loading ◽  
Vis Spectroscopy ◽  
Zero Order Release ◽  
Plausible Mechanism ◽  
Ph Conditions ◽  
Kinetics Of ◽  
Potential Use

Nanoparticles (NPs) have been widely explored for delivering doxorubicin (DOX), an anticancer drug, to minimize cardiotoxicity. However, their efficiency is marred by a necessity to chemically modify DOX, NPs, or both and low deposition of the administered NPs on tumors. Therefore, alternative strategies should be developed to improve therapeutic efficacy and decrease toxicity. Here we report the possibility of employing a monolithic nanoporous gold (np-Au) rod as an implant for delivering DOX. The np-Au has very high DOX encapsulation efficiency (>98%) with maximum loading of 93.4 mg cm−3 without any chemical modification required of DOX or np-Au. We provide a plausible mechanism for the high loading of DOX in np-Au. The DOX sustained release for 26 days from np-Au in different pH conditions at 37 °C, which was monitored using UV-Vis spectroscopy. Additionally, we encased the DOX-loaded np-Au with rapamycin (RAPA)-trapped poly(D,L-lactide-co-glycolide) (PLGA) to fabricate an np-Au@PLGA/RAPA implant and optimized the combinatorial release of DOX and RAPA. Further exploiting the effect of the protein corona around np-Au and np-Au@PLGA/RAPA showed zero-order release kinetics of DOX. This work proves that the np-Au-based implant has the potential to be used as a DOX carrier of potential use in cancer treatment.

Fabrication of nanoporous gold thin films on silicon substrate by multilayer deposition of Au and Ag

2009 ◽  
Vol 484 (1-2) ◽  
pp. 28-32 ◽  
Author(s):  
Minho Kim ◽  
Woo-Jin Ha ◽  
Jin-Woo Anh ◽  
Hye-Sung Kim ◽  
Sang-Whan Park ◽  
...  
Keyword(s):  
Thin Films ◽  
Silicon Substrate ◽  
Nanoporous Gold ◽  
Multilayer Deposition ◽  
Gold Thin Films

Polarization-dependent ultrafast plasmon relaxation dynamics in nanoporous gold thin films and nanowires

2019 ◽  
Vol 52 (22) ◽  
pp. 225103 ◽  
Author(s):  
Domantas Peckus ◽  
Adrien Chauvin ◽  
Tomas Tamulevičius ◽  
Mindaugas Juodėnas ◽  
Junjun Ding ◽  
...  
Keyword(s):  
Thin Films ◽  
Nanoporous Gold ◽  
Relaxation Dynamics ◽  
Gold Thin Films
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