scholarly journals A perspective on the growth-only zone, the secondary nucleation threshold and crystal size distribution in solution crystallisation

CrystEngComm ◽  
2016 ◽  
Vol 18 (3) ◽  
pp. 369-378 ◽  
Author(s):  
Terence L. Threlfall ◽  
Simon J. Coles
Keyword(s):  
Size Distribution ◽  
Crystal Size ◽  
Crystal Size Distribution ◽  
Solubility Curve ◽  
Secondary Nucleation ◽  
Metastable Zone

The metastable zone between the solubility curve and the crystallisation curve can be divided into two regions, separated by the secondary nucleation threshold.

Membrane assisted cooling crystallization: Process model, nucleation, metastable zone, and crystal size distribution

AIChE Journal ◽  
2015 ◽  
Vol 62 (3) ◽  
pp. 829-841 ◽  
Author(s):  
Xiaobin Jiang ◽  
Dapeng Lu ◽  
Wu Xiao ◽  
Xuehua Ruan ◽  
Jian Fang ◽  
...  
Keyword(s):  
Size Distribution ◽  
Process Model ◽  
Crystal Size ◽  
Crystallization Process ◽  
Crystal Size Distribution ◽  
Cooling Crystallization ◽  
Metastable Zone

scholarly journals Tunable Protein Crystal Size Distribution via Continuous Slug-Flow Crystallization with Spatially Varying Temperature

CrystEngComm ◽  
2021 ◽  
Author(s):  
Nicholas Mozdzierz ◽  
Moo Sun Hong ◽  
Yongkyu Lee ◽  
Moritz Benisch ◽  
Mo Jiang ◽  
...  
Keyword(s):  
Product Quality ◽  
Size Distribution ◽  
Slug Flow ◽  
Crystal Size ◽  
Quality Attributes ◽  
Crystal Size Distribution ◽  
Protein Crystal ◽  
Manufacturing Cost ◽  
Spatially Varying

Accompanied with the growth of the biopharmaceuticals market has been an interest in developing processes with increased control of product quality attributes at low manufacturing cost, with one of the...

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