An ionic liquid catalyzed reusable protocol for one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-one under mild conditions

2015 ◽  
Vol 39 (12) ◽  
pp. 9693-9699 ◽  
Author(s):  
S. Nagarajan ◽  
Tanveer Mahamadali Shaikh ◽  
Elango Kandasamy
Keyword(s):  
Ionic Liquid ◽  
Catalytic Activity ◽  
Functional Group ◽  
One Pot ◽  
Mild Conditions ◽  
One Pot Synthesis ◽  
Synthetic Utility

This article describes an efficient protocol for the syntheses of 2,3-dihydroquinazolinones. The synthetic utility of this methodology has been demonstrated with 30 different substrates. The reaction showed good functional group tolerance and high levels of catalytic activity.

Fe(III)/l-Valine-Catalyzed One-Pot Synthesis of N-Sulfinyl- and N-Sulfonylimines via Oxidative Cascade Reaction of Alcohols with Sulfinamides or Sulfonamides

Synlett ◽  
2018 ◽  
Vol 29 (09) ◽  
pp. 1232-1238
Author(s):  
Guofu Zhang ◽  
Yunzhe Xing ◽  
Shengjun Xu ◽  
Chengrong Ding ◽  
Shang Shan
Keyword(s):  
Catalytic System ◽  
Functional Group ◽  
Cascade Reaction ◽  
One Pot ◽  
Mild Conditions ◽  
One Pot Synthesis ◽  
Oxidation Of Alcohols

An efficient Fe(III), l-valine, and 4-OH-TEMPO catalytic system was found for the oxidation of alcohols followed by condensation with sulfinamide or sulfonamide in one pot for the synthesis of N-sulfinyl- and N-sulfonylimines compounds under mild conditions. This transformation accommodates a variety of substrates, shows high functional-group tolerance, and affords the corresponding products in good to excellent yields.

One-pot synthesis of 3D Cu2S–MoS2 nanocomposites by an ionic liquid-assisted strategy with high photocatalytic activity

2019 ◽  
Vol 43 (1) ◽  
pp. 269-276 ◽  
Author(s):  
Ya Chen ◽  
Penghe Su ◽  
Xiaotong Liu ◽  
Hongchi Liu ◽  
Baolin Zhu ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Photocatalytic Activity ◽  
Catalytic Activity ◽  
Hydrothermal Method ◽  
High Photocatalytic Activity ◽  
One Pot ◽  
One Pot Synthesis ◽  
One Step

Cu2S–MoS2 nanocomposites are synthesised by a one-step hydrothermal method and show better catalytic activity than Cu2S and MoS2 monomers.

scholarly journals Recyclable [Ce(l-Pro)2]2 (Oxa) used as Heterogeneous Catalyst: One-Pot Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones in Ethanol

Synthesis ◽  
2017 ◽  
Vol 49 (23) ◽  
pp. 5143-5148 ◽  
Author(s):  
Ramesh Katla ◽  
Rakhi Chowrasia ◽  
Caren da Silva ◽  
Aline de Oliveira ◽  
Beatriz dos Santos ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Heterogeneous Catalyst ◽  
Significant Loss ◽  
One Pot ◽  
Mild Conditions ◽  
One Pot Synthesis ◽  
The One ◽  
Recyclable Heterogeneous Catalyst

[Ce(l-Pro)2]2 (Oxa) was used as a recyclable heterogeneous catalyst under mild conditions for the preparation of 2-aryl-2,3-dihydroquinazolin-4(1H)-one derivatives. The one-pot protocol proceeds in ethanol using anthranilamide with several aldehydes at 50–55 °C. The catalyst can be recycled and reused three cycles without significant loss of catalytic activity.

An ionic liquid catalyzed probase method for one-pot synthesis of α,β-unsaturated esters from esters and aldehydes under mild conditions

2017 ◽  
Vol 19 (20) ◽  
pp. 4838-4848 ◽  
Author(s):  
Gang Wang ◽  
Yiming Xu ◽  
Suojiang Zhang ◽  
Zengxi Li ◽  
Chunshan Li
Keyword(s):  
Ionic Liquid ◽  
Unsaturated Ester ◽  
Ester Synthesis ◽  
One Pot ◽  
Unsaturated Esters ◽  
Mild Conditions ◽  
One Pot Synthesis

An ionic liquid catalyzed probase method for unsaturated ester synthesis under mild conditions was reported.

scholarly journals Bismuth (III) Salts Promoted and Ionic Liquid Assisted an Efficient and Environmentally Benign One-Pot Synthesis of 1,5-Benzodiazepine Derivatives

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Atul Chaskar ◽  
Latika Patil ◽  
Kiran Phatangare ◽  
Vikas Padalkar ◽  
Santosh Takale
Keyword(s):  
Ionic Liquid ◽  
Environmentally Benign ◽  
One Pot ◽  
Mild Conditions ◽  
Condensation Reactions ◽  
One Pot Synthesis ◽  
Benzodiazepine Derivatives ◽  
Efficient Environment

1,5-Benzodiazepine derivatives were synthesized by the condensation reactions of o-phenylenediamine and ketones catalyzed by bismuth (III) salts under mild conditions. This method is easy, efficient, environment and eco-friendly, free of toxic catalysts, and gives good to excellent yields of 1, 5-benzodiazepines.

Copper-Catalyzed One-Pot Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones from 2-Nitrobenzonitriles and Carbonyl Compounds Mediated by Diboronic Acid in Methanol–Water

Synlett ◽  
2019 ◽  
Vol 31 (03) ◽  
pp. 275-279 ◽  
Author(s):  
Qixing Liu ◽  
Yuebo Sui ◽  
Yin Zhang ◽  
Kaili Zhang ◽  
Yongsheng Chen ◽  
...  
Keyword(s):  
Aqueous Medium ◽  
Carbonyl Compounds ◽  
Functional Group ◽  
One Pot ◽  
Mild Conditions ◽  
One Pot Synthesis

A copper-catalyzed one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones with diboronic acid as a reductant in an aqueous medium is described. Various 2,3-dihydroquinazolin-4(1H)-ones were prepared with good functional-group tolerance in good yields under mild conditions from readily available 2-nitrobenzonitriles and various carbonyl compounds.

One-Pot Synthesis of Polysubstituted Imidazoles Based on Pd(OAc)2/Ce(SO4)2/Bi(NO3)3 Trimetallic Cascade of Decarboxylation/Wacker-Type Oxidation/Debus–Radziszewski Reaction

Synthesis ◽  
2019 ◽  
Vol 51 (17) ◽  
pp. 3221-3230 ◽  
Author(s):  
Wei Sun ◽  
Mingjuan Zhang ◽  
Peilang Li ◽  
Yiqun Li
Keyword(s):  
Catalytic System ◽  
Multicomponent Reaction ◽  
Functional Group ◽  
Cascade Process ◽  
One Pot ◽  
Aryl Aldehydes ◽  
Mild Conditions ◽  
One Pot Synthesis ◽  
System A

A novel and highly efficient one-pot synthesis of polysubstituted imidazoles from α-hydroxyphenylacetic acids, diphenylacetylene, and amines has been achieved by Pd(OAc)2/Ce(SO4)2/Bi(NO3)3 trimetallic catalytic system. A series of control experiments showed that this overall reaction occurs through a one-pot cascade process combining the steps of decarboxylation of α-hydroxyphenylacetic acids, Wacker-type oxidation of diphenylacetylene, and Debus–Radziszewski annulation of aryl aldehydes and benzil generated in situ, as well as amines. This reaction represents a novel multicomponent reaction using α-hydroxyphenylacetic acids and diphenylacetylene as sources of aryl aldehydes and a β-diketone. This process exhibits a broad substrate scope and a good functional group tolerance to assemble the corresponding polysubstituted imidazoles in excellent yields (72–88%) under mild conditions.

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