Tough biodegradable chitosan–gelatin hydrogels via in situ precipitation for potential cartilage tissue engineering

Chitosan/gelatin composite hydrogels with high strength are prepared by a precipitation method, possess controlled structures and biodegradability, support chondrocyte adhesion and growth, and may have potentials to cartilage tissue engineering.

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New “Tribo-bioreactor” for In-situ Monitoring of the Mechanical Stress Transmission at the Cellular Level: Application to Cartilage Tissue Engineering

Biotribology ◽

10.1016/j.biotri.2020.100158 ◽

2021 ◽

Vol 25 ◽

pp. 100158

Author(s):

Amira Hannoun ◽

Emeline Perrier-Groult ◽

Livia Cureu ◽

Marielle Pasdeloup ◽

Yves Berthier ◽

...

Keyword(s):

Tissue Engineering ◽

Mechanical Stress ◽

Cartilage Tissue Engineering ◽

Cellular Level ◽

In Situ Monitoring ◽

Cartilage Tissue ◽

Stress Transmission

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Migration and differentiation potential of mesenchymal stem cells from patients with late osteoarthritis towards in situ joint cartilage tissue engineering

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2013.02.640 ◽

2013 ◽

Vol 21 ◽

pp. S309 ◽

Cited By ~ 1

Author(s):

J. Ringe ◽

K. Gulich ◽

T. Dehne ◽

K. Andreas ◽

G.-R. Burmester ◽

...

Keyword(s):

Tissue Engineering ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Cartilage Tissue Engineering ◽

Cartilage Tissue ◽

Joint Cartilage ◽

Differentiation Potential

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Injectable In Situ Self-Cross-Linking Hydrogels Based on Poly(l-glutamic acid) and Alginate for Cartilage Tissue Engineering

Biomacromolecules ◽

10.1021/bm501313t ◽

2014 ◽

Vol 15 (12) ◽

pp. 4495-4508 ◽

Cited By ~ 113

Author(s):

Shifeng Yan ◽

Taotao Wang ◽

Long Feng ◽

Jie Zhu ◽

Kunxi Zhang ◽

...

Keyword(s):

Tissue Engineering ◽

Glutamic Acid ◽

Cartilage Tissue Engineering ◽

Cartilage Tissue ◽

Cross Linking

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Injectable in situ-forming hydrogel for cartilage tissue engineering

Journal of Materials Chemistry B ◽

10.1039/c3tb20105h ◽

2013 ◽

Vol 1 (26) ◽

pp. 3314 ◽

Cited By ~ 28

Author(s):

Jin Seon Kwon ◽

So Mi Yoon ◽

Doo Yeon Kwon ◽

Da Yeon Kim ◽

Guo Zhe Tai ◽

...

Keyword(s):

Tissue Engineering ◽

Cartilage Tissue Engineering ◽

Cartilage Tissue ◽

In Situ Forming

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Applications of Hydrogel with Special Physical Properties in Bone and Cartilage Regeneration

Materials ◽

10.3390/ma14010235 ◽

2021 ◽

Vol 14 (1) ◽

pp. 235

Author(s):

Hua Lin ◽

Cuilan Yin ◽

Anchun Mo ◽

Guang Hong

Keyword(s):

Tissue Engineering ◽

Physical Properties ◽

Cartilage Tissue Engineering ◽

Antibacterial Properties ◽

High Strength ◽

Cartilage Regeneration ◽

Cartilage Tissue ◽

Medical Progress ◽

Extracellular Matrix Components ◽

And Cartilage

Hydrogel is a polymer matrix containing a large amount of water. It is similar to extracellular matrix components. It comes into contact with blood, body fluids, and human tissues without affecting the metabolism of organisms. It can be applied to bone and cartilage tissues. This article introduces the high-strength polymer hydrogel and its modification methods to adapt to the field of bone and cartilage tissue engineering. From the perspective of the mechanical properties of hydrogels, the mechanical strength of hydrogels has experienced from the weak-strength traditional hydrogels to the high-strength hydrogels, then the injectable hydrogels were invented and realized the purpose of good fluidity before the use of hydrogels and high strength in the later period. In addition, specific methods to give special physical properties to the hydrogel used in the field of bone and cartilage tissue engineering will also be discussed, such as 3D printing, integrated repair of bone and cartilage tissue, bone vascularization, and osteogenesis hydrogels that regulate cell growth, antibacterial properties, and repeatable viscosity in humid environments. Finally, we explain the main reasons and contradictions in current applications, look forward to the research prospects in the field of bone and cartilage tissue engineering, and emphasize the importance of conducting research in this field to promote medical progress.

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