LC-ESI-TOF-MS-based metabolomic analysis of ginsenoside Rd-induced anaphylactoid reaction in mice

RSC Advances ◽  
2016 ◽  
Vol 6 (23) ◽  
pp. 19545-19554 ◽  
Author(s):  
Xiaoyan Lu ◽  
Xueping Lian ◽  
Jie zheng ◽  
Ni Ai ◽  
Cai Ji ◽  
...  

A ginsenoside Rd-induced anaphylactoid reaction in mice was investigated by LC-ESI-TOF-MS-based metabolomic analysis as well as general toxicological assessments.

2015 ◽  
Vol 30 (1) ◽  
pp. 48-54 ◽  
Author(s):  
Yang Wang ◽  
Desheng Liu ◽  
Yue Li ◽  
Lei Guo ◽  
Yinghua Cui ◽  
...  

2010 ◽  
Vol 31 (5) ◽  
pp. 399-410 ◽  
Author(s):  
Kimberly J. Ralston-Hooper ◽  
Jiri Adamec ◽  
Amber Jannash ◽  
Robert Mollenhauer ◽  
Hugo Ochoa-Acuña ◽  
...  

2021 ◽  
Vol 503 ◽  
pp. 108299
Author(s):  
Maojin Lan ◽  
Mingfeng Weng ◽  
Zhenyu Lin ◽  
Jian Wang ◽  
Feng Zhao ◽  
...  

Metabolomics ◽  
2008 ◽  
Vol 5 (2) ◽  
pp. 229-238 ◽  
Author(s):  
Ming-Zhu Ding ◽  
Jing-Sheng Cheng ◽  
Wen-Hai Xiao ◽  
Bin Qiao ◽  
Ying-Jin Yuan

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Hyuck Joon Kwon ◽  
Yoshihiro Ohmiya

Prechondrogenic condensation is a critical step for skeletal pattern formation. Recent studies reported that ATP oscillations play an essential role in prechondrogenic condensation. However, the molecular mechanism to underlie ATP oscillations remains poorly understood. In the present study, it was investigated how changes in metabolites are implicated in ATP oscillations during chondrogenesis by using capillary electrophoresis time-of-flight mass spectrometry (CE-TOF-MS). CE-TOF-MS detected 93 cationic and 109 anionic compounds derived from known metabolic pathways. 15 cationic and 18 anionic compounds revealed significant change between peak and trough of ATP oscillations. These results implicate that glycolysis, mitochondrial respiration and uronic acid pathway oscillate in phase with ATP oscillations, while PPRP and nucleotides synthesis pathways oscillate in antiphase with ATP oscillations. This suggests that the ATP-producing glycolysis and mitochondrial respiration oscillate in antiphase with the ATP-consuming PPRP/nucleotide synthesis pathway during chondrogenesis.


2012 ◽  
Vol 63 ◽  
pp. 128-134 ◽  
Author(s):  
S. Fernández-Arroyo ◽  
A. Gómez-Martínez ◽  
L. Rocamora-Reverte ◽  
R. Quirantes-Piné ◽  
A. Segura-Carretero ◽  
...  

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