Acetate ions enhance load and stability of doxorubicin onto PEGylated nanodiamond for selective tumor intracellular controlled release and therapy

2016 ◽  
Vol 8 (9) ◽  
pp. 956-967 ◽  
Author(s):  
Lin Li ◽  
Lu Tian ◽  
Wenjing Zhao ◽  
Yingqi Li ◽  
Binsheng Yang
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Tumor Cells ◽  
Cancer Chemotherapy ◽  
Therapeutic Efficacy ◽  
Normal Tissue ◽  
Delivery Device ◽  
Drug Delivery Device

A successful drug delivery device for cancer chemotherapy should ideally be able to load drugs highly, bring the drug preferentially into tumor cells and reduce its distribution in normal tissue to enhance therapeutic efficacy.

scholarly journals Novel Drug Delivery Device Using Silicone: Controlled Release of Insoluble Drugs or Two Kinds of Water-Soluble Drugs

2003 ◽  
Vol 51 (1) ◽  
pp. 15-19 ◽  
Author(s):  
Masako Kajihara ◽  
Toshihiko Sugie ◽  
Hiroo Maeda ◽  
Akihiko Sano ◽  
Keiji Fujioka ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Water Soluble ◽  
Delivery Device ◽  
Drug Delivery Device ◽  
Water Soluble Drugs ◽  
Insoluble Drugs ◽  
Novel Drug

On-demand controlled release of docetaxel from a battery-less MEMS drug delivery device

Lab on a Chip ◽  
2011 ◽  
Vol 11 (16) ◽  
pp. 2744 ◽  
Author(s):  
Fatemeh Nazly Pirmoradi ◽  
John K. Jackson ◽  
Helen M. Burt ◽  
Mu Chiao
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Delivery Device ◽  
Drug Delivery Device ◽  
On Demand

scholarly journals Preparation and Characteristics of a Novel Sustained and Controlled Release Drug Delivery Device by Plasma Technique

2016 ◽  
Vol 29 (3) ◽  
pp. 447-450 ◽  
Author(s):  
Yukinori Yamauchi ◽  
Masayuki Kuzuya ◽  
Yasushi Sasai ◽  
Naoki Doi ◽  
Shin-ichi Kondo
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Delivery Device ◽  
Drug Delivery Device ◽  
Plasma Technique ◽  
Release Drug

scholarly journals Controlled release kinetics from a surface modified microgel-based reservoir device

2015 ◽  
Vol 3 (12) ◽  
pp. 2516-2521 ◽  
Author(s):  
Siyuan Guo ◽  
Yongfeng Gao ◽  
Menglian Wei ◽  
Qiang Matthew Zhang ◽  
Michael J. Serpe
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Drug Release ◽  
Release Kinetics ◽  
Fine Tuning ◽  
Delivery Device ◽  
Drug Delivery Device ◽  
Drug Release Kinetics ◽  
Surface Modified

Deposition of Si-based layers on top of a polymer-based “drug” delivery device allows fine-tuning of “drug” release kinetics.

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