Synthesis, characterization and biological evaluation of a novel biscarboxymethyl-modified tetraphenylchlorin compound for photodynamic therapy

RSC Advances ◽  
2016 ◽  
Vol 6 (31) ◽  
pp. 26186-26191 ◽  
Author(s):  
Pingyong Liao ◽  
Xianghua Zhang ◽  
Lijun Zhang ◽  
Xinrong Wang ◽  
Wei Zhu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Antitumor Agent ◽  
Biological Evaluation

Compound BCTC is an effective and a highly promising antitumor agent for photodynamic therapy.

Synthesis and Biological Evaluation of New Amino Acids Structurally Related to the Antitumor Agent Acivicin.

ChemInform ◽  
2004 ◽  
Vol 35 (2) ◽  
Author(s):  
Paola Conti ◽  
Gabriella Roda ◽  
Helena Stabile ◽  
Maria Antonietta Vanoni ◽  
Bruno Curti ◽  
...  
Keyword(s):  
Amino Acids ◽  
Antitumor Agent ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of peptidomimetics containing the tryptamine moiety as a potential antitumor agent

RSC Advances ◽  
2015 ◽  
Vol 5 (20) ◽  
pp. 15597-15602 ◽  
Author(s):  
Xiaohui Wang ◽  
Haihuan Su ◽  
Changshui Chen ◽  
Xiufang Cao
Keyword(s):  
Cell Proliferation ◽  
Cell Lines ◽  
Antitumor Agent ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation ◽  
Potential Antitumor

A series of novel peptidomimetics bearing tryptamine moiety were designed, synthesized, and evaluated for their inhibition activities against cell proliferation (HepG2, Huh-7, A875 and BEL-7402/5-FU cell lines).

2,4,6-Triarylchalcogenopyrylium Dyes Related in Structure to the Antitumor Agent AA1 as in Vitro Sensitizers for the Photodynamic Therapy of Cancer

1999 ◽  
Vol 42 (19) ◽  
pp. 3942-3952 ◽  
Author(s):  
Kristi A. Leonard ◽  
Marina I. Nelen ◽  
Linda T. Anderson ◽  
Scott L. Gibson ◽  
Russell Hilf ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Antitumor Agent ◽  
Photodynamic Therapy Of Cancer

New RuIIpincer complexes: synthesis, characterization and biological evaluation for photodynamic therapy

2016 ◽  
Vol 45 (45) ◽  
pp. 18333-18345 ◽  
Author(s):  
Leila Tabrizi ◽  
Hossein Chiniforoshan
Keyword(s):  
Photodynamic Therapy ◽  
Dna Binding ◽  
Biological Evaluation ◽  
Pincer Complexes ◽  
Dna Photocleavage ◽  
Ct Dna

The CT DNA binding, DNA photocleavage and photocytotoxicity of ruthenium(ii)–NCN pincer complexes were investigated.

Synthesis and biological evaluation of polyamine-porphyrin conjugates as potential agents in photodynamic therapy (PDT)

2002 ◽  
Vol 06 (02) ◽  
pp. 130-134 ◽  
Author(s):  
François Lamarche ◽  
Vincent Sol ◽  
Yi-Ming Huang ◽  
Robert Granet ◽  
Michel Guilloton ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Biological Evaluation ◽  
Myelogenous Leukemia ◽  
Leukemia Cells ◽  
Malignant Cells ◽  
Photofrin Ii ◽  
New Class ◽  
Human Chronic Myelogenous Leukemia ◽  
Chronic Myelogenous Leukemia Cells ◽  
Synthesis And Biological Evaluation

A new class of porphyrins bearing natural polyamines has been designed in order to target the photosensitizers towards malignant cells. We report here the synthesis of spermidine and spermine porphyrins. The photocytotoxicity of these compounds against K562 human chronic myelogenous leukemia cells has been evaluated and compared to Photofrin II®.

Design, synthesis, and biological evaluation of folic acid targeted tetraphenylporphyrin as novel photosensitizers for selective photodynamic therapy

2005 ◽  
Vol 13 (8) ◽  
pp. 2799-2808 ◽  
Author(s):  
Raphaël Schneider ◽  
Frédéric Schmitt ◽  
Céline Frochot ◽  
Yves Fort ◽  
Natacha Lourette ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Folic Acid ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation
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