Synthesis and biological evaluation of polyamine-porphyrin conjugates as potential agents in photodynamic therapy (PDT)

2002 ◽  
Vol 06 (02) ◽  
pp. 130-134 ◽  
Author(s):  
François Lamarche ◽  
Vincent Sol ◽  
Yi-Ming Huang ◽  
Robert Granet ◽  
Michel Guilloton ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Biological Evaluation ◽  
Myelogenous Leukemia ◽  
Leukemia Cells ◽  
Malignant Cells ◽  
Photofrin Ii ◽  
New Class ◽  
Human Chronic Myelogenous Leukemia ◽  
Chronic Myelogenous Leukemia Cells ◽  
Synthesis And Biological Evaluation

A new class of porphyrins bearing natural polyamines has been designed in order to target the photosensitizers towards malignant cells. We report here the synthesis of spermidine and spermine porphyrins. The photocytotoxicity of these compounds against K562 human chronic myelogenous leukemia cells has been evaluated and compared to Photofrin II®.

scholarly journals Cytotoxic effects of the compound cis-tetraammine(oxalato)ruthenium(III) dithionate on K-562 human chronic myelogenous leukemia cells

SpringerPlus ◽  
2014 ◽  
Vol 3 (1) ◽  
pp. 301 ◽  
Author(s):  
Flávia de Pereira ◽  
Aliny de Lima ◽  
Cesar Augusto Sam Tiago Vilanova-Costa ◽  
Wanessa Pires ◽  
Alessandra de Santana Braga Barbosa Ribeiro ◽  
...  
Keyword(s):  
Chronic Myelogenous Leukemia ◽  
Myelogenous Leukemia ◽  
Leukemia Cells ◽  
Cytotoxic Effects ◽  
Human Chronic Myelogenous Leukemia ◽  
Chronic Myelogenous Leukemia Cells

In vitro activity of resorcinarene–chlorambucil conjugates for therapy in human chronic myelogenous leukemia cells

2019 ◽  
Vol 45 (4) ◽  
pp. 683-688 ◽  
Author(s):  
Sonia Mendoza-Cardozo ◽  
Luis D. Pedro-Hernández ◽  
Ulises Organista-Mateos ◽  
Luis Isaac Allende-Alarcón ◽  
Elena Martínez-Klimova ◽  
...  
Keyword(s):  
Chronic Myelogenous Leukemia ◽  
Myelogenous Leukemia ◽  
Vitro Activity ◽  
Leukemia Cells ◽  
In Vitro Activity ◽  
Human Chronic Myelogenous Leukemia ◽  
Chronic Myelogenous Leukemia Cells

Synthesis and Biological Evaluation of Thioglycosylated meso-Arylporphyrins

1999 ◽  
Vol 03 (01) ◽  
pp. 1-4 ◽  
Author(s):  
ISABELLE SYLVAIN ◽  
RACHIDA BENHADDOU ◽  
VINCENT CARRE ◽  
SYLVAIN COTTAZ ◽  
HUGUES DRIGUEZ ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Biological Evaluation ◽  
Malignant Cells ◽  
Yeast Saccharomyces Cerevisiae ◽  
New Class ◽  
Synthesis And Biological Evaluation

A new class of porphyrins bearing thioglycosyl groups is presented in order to improve targeting of malignant cells and resistance to glycosidases. These compounds were synthesized in four steps. They produced 1 O 2 and their photocytotoxicity against the yeast Saccharomyces cerevisiae was compared with the effect of haematoporphyrin.

Total synthesis of VIM-2 ganglioside isolated from human chronic myelogenous leukemia cells

1996 ◽  
Vol 281 (2) ◽  
pp. 237-252 ◽  
Author(s):  
Taro Ehara ◽  
Akihiko Kameyama ◽  
Yutaka Yamada ◽  
Hideharu Ishida ◽  
Makoto Kiso ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Chronic Myelogenous Leukemia ◽  
Myelogenous Leukemia ◽  
Leukemia Cells ◽  
Human Chronic Myelogenous Leukemia ◽  
Chronic Myelogenous Leukemia Cells
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