Synthesis and biological evaluation of 3-amino-3-hydroxymethyloxindoles as potential anti-cancer agents
Keyword(s):
A series of substituted 3-amino-3-hydroxymethyloxindoles synthesized through a multi-component approach showed anticancer potency. The most potent compound 5m inhibits SJSA-1 proliferation with an IC50 of 3.14 μM. It can also induce time- and dose-dependent apoptosis.
2017 ◽
Vol 27
(9)
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pp. 1923-1928
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2020 ◽
2020 ◽
2021 ◽
Vol 47
(4)
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pp. 954-962
2012 ◽
Vol 57
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pp. 311-322
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2012 ◽
Vol 22
(23)
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pp. 7268-7271
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Keyword(s):
2018 ◽
Vol 26
(4)
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pp. 884-890
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