scholarly journals Highly efficient one-pot tandem Friedlander annulation and chemo-selective Csp3–H functionalization under calcium catalysis

RSC Advances ◽  
2017 ◽  
Vol 7 (31) ◽  
pp. 18874-18882 ◽  
Author(s):  
Garima Singh ◽  
Srinivasarao Yaragorla
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
Highly Efficient ◽  
Solvent Free Conditions ◽  
Friedlander Synthesis ◽  
First Time ◽  
Calcium Catalysis

Highly efficient and regioselective Friedlander synthesis of 2-methyl-3-acyl quinolines and their chemoselective Csp3–H functionalization is described for the first time using Ca(OTf)2 as the sustainable catalyst under solvent free conditions with atom and step economy.

A highly efficient and green approach for the synthesis of pyrimido[4,5-b]quinolines using N,N-diethyl-N-sulfoethanaminium chloride

2021 ◽  
Vol 76 (2) ◽  
pp. 85-90
Author(s):  
Abdolkarim Zare ◽  
Manije Dianat
Keyword(s):  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Catalyst Amount ◽  
Green Protocol ◽  
Highly Efficient ◽  
Green Approach ◽  
Solvent Free Conditions ◽  
The One ◽  
High Yields

Abstract A highly efficient and green protocol for the synthesis of pyrimido[4,5-b]quinolines has been described. The one-pot multicomponent reaction of dimedone with arylaldehydes and 6-amino-1,3-dimethyluracil in the presence of N,N-diethyl-N-sulfoethanaminium chloride ([Et3N–SO3H][Cl]) as an ionic liquid (IL) catalyst under solvent-free conditions afforded the mentioned compounds in high yields and short reaction times. Our protocol is superior to many of the reported protocols in terms of two or more of these factors: the reaction times, yields, conditions (solvent-free versus usage of organic solvents), temperature and catalyst amount.

A straightforward one-pot synthesis of bioactive N-aryl oxazolidin-2-ones via a highly efficient Fe3O4@SiO2-supported acetate-based butylimidazolium ionic liquid nanocatalyst under metal- and solvent-free conditions

2017 ◽  
Vol 19 (16) ◽  
pp. 3801-3812 ◽  
Author(s):  
Radhika Gupta ◽  
Manavi Yadav ◽  
Rashmi Gaur ◽  
Gunjan Arora ◽  
Rakesh Kumar Sharma
Keyword(s):  
Ionic Liquid ◽  
Solvent Free ◽  
Magnetic Nanocatalyst ◽  
One Pot ◽  
Supported Ionic Liquid ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Solvent Free Conditions

A supported ionic liquid-based magnetic nanocatalyst has been fabricated for the formation of pharmaceutically important N-aryl oxazolidin-2-ones.

Uncatalyzed Synthesis of Unsymmetrical Indole-substituted Methane Derivatives via One-pot Multicomponent Reactions under Solvent-free Conditions

2021 ◽  
Vol 18 ◽  
Author(s):  
Shiyin Li ◽  
Xinru Lin ◽  
Xiling Gao ◽  
Wangyu Zeng ◽  
Xiaoyi Wu ◽  
...  
Keyword(s):  
Multicomponent Reactions ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Experimental Results ◽  
Synthetic Method ◽  
One Pot ◽  
Solvent Free Conditions ◽  
First Time

For the first time, one-pot multi-component reactions containing indole, aromatic aldehydes, and dimedone have been achieved in the absence of any catalyst under solvent-free conditions. A class of unsymmetrical indole-substituted methane derivatives and symmetrical diindolylmethanes have been synthesized through this green organic synthetic method. Based on experimental results, a reasonable mechanism for this condensation is emphasized here.

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