scholarly journals Biomonitoring method for the analysis of chromium and cobalt in human whole blood using inductively coupled plasma-kinetic energy discrimination-mass spectrometry (ICP-KED-MS)

2017 ◽  
Vol 9 (23) ◽  
pp. 3464-3476 ◽  
Author(s):  
Joaudimir Castro Georgi ◽  
Yuliya L. Sommer ◽  
Cynthia D. Ward ◽  
Po-Yung Cheng ◽  
Robert L. Jones ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Kinetic Energy ◽  
Whole Blood ◽  
Inductively Coupled Plasma ◽  
Total Chromium ◽  
Human Whole Blood ◽  
Inductively Coupled ◽  
Plasma Kinetic ◽  
Icp Ms ◽  
Energy Discrimination

An ICP-MS method to measure total chromium and cobalt in whole blood is validated and described.

Single Particle Inductively Coupled Plasma Mass Spectrometry: Investigating Nonlinear Response Observed in Pulse Counting Mode and Extending the Linear Dynamic Range by Compensating for Dead Time Related Count Losses on a Microsecond Timescale

2019 ◽  
Author(s):  
Ingo Strenge ◽  
Carsten Engelhard
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Nonlinear Response ◽  
Dynamic Range ◽  
Dead Time ◽  
Inorganic Nanoparticles ◽  
Linear Dynamic Range ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

<p>The article demonstrates the importance of using a suitable approach to compensate for dead time relate count losses (a certain measurement artefact) whenever short, but potentially strong transient signals are to be analysed using inductively coupled plasma mass spectrometry (ICP-MS). Findings strongly support the theory that inadequate time resolution, and therefore insufficient compensation for these count losses, is one of the main reasons for size underestimation observed when analysing inorganic nanoparticles using ICP-MS, a topic still controversially discussed.</p>

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