scholarly journals Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-α and ABHD6 inhibitors

MedChemComm ◽  
2017 ◽  
Vol 8 (5) ◽  
pp. 982-988 ◽  
Author(s):  
Hui Deng ◽  
Tom van der Wel ◽  
Richard J. B. H. N. van den Berg ◽  
Adrianus M. C. H. van den Nieuwendijk ◽  
Freek J. Janssen ◽  
...  
Keyword(s):  
Enantioselective Synthesis ◽  
Diacylglycerol Lipase ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Dual Inhibitors

The enantioselective synthesis and structure–activity relationships of deoxy-iminosugar-based triazole ureas as dual inhibitors of DAGLα and ABHD6 were reported.

scholarly journals Comprehensive Analysis of Structure–Activity Relationships of α-Ketoheterocycles as sn-1-Diacylglycerol Lipase α Inhibitors

2015 ◽  
Vol 58 (24) ◽  
pp. 9742-9753 ◽  
Author(s):  
Freek J. Janssen ◽  
Marc P. Baggelaar ◽  
Jessica J. A. Hummel ◽  
Herman S. Overkleeft ◽  
Benjamin F. Cravatt ◽  
...  
Keyword(s):  
Comprehensive Analysis ◽  
Diacylglycerol Lipase ◽  
Structure Activity Relationships ◽  
Structure Activity

Novel Dual Inhibitors of 5-Lipoxygenase and Thromboxane A2 Synthetase: Synthesis and Structure-Activity Relationships of 3-Pyridylmethyl-Substituted 2-Amino-6-hydroxybenzothiazole Derivatives

1994 ◽  
Vol 37 (19) ◽  
pp. 3062-3070 ◽  
Author(s):  
Shigeki Hibi ◽  
Yasushi Okamoto ◽  
Katsuya Tagami ◽  
Hirotoshi Numata ◽  
Naoki Kobayashi ◽  
...  
Keyword(s):  
Thromboxane A2 ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Dual Inhibitors

Synthesis and structure–activity relationships of PI3K/mTOR dual inhibitors from a series of 2-amino-4-methylpyrido[2,3- d ]pyrimidine derivatives

2014 ◽  
Vol 24 (18) ◽  
pp. 4538-4541 ◽  
Author(s):  
Fangbin Han ◽  
Songwen Lin ◽  
Peng Liu ◽  
Jing Tao ◽  
Chongqin Yi ◽  
...  
Keyword(s):  
Pyrimidine Derivatives ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Dual Inhibitors

scholarly journals Structure-Activity Relationships (SAR) Research of Thiourea Derivatives as Dual Inhibitors Targeting both HIV-1 Capsid and Human Cyclophilin A

2010 ◽  
Vol 76 (1) ◽  
pp. 25-33 ◽  
Author(s):  
Kan Chen ◽  
Zhiwu Tan ◽  
Meizi He ◽  
Jiebo Li ◽  
Shixing Tang ◽  
...  
Keyword(s):  
Cyclophilin A ◽  
Thiourea Derivatives ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Dual Inhibitors ◽  
Hiv 1

Structure-Activity Relationships of MDMA-Like Substances

1989 ◽  
Author(s):  
David E. Nichols ◽  
◽  
Robert Oberlender
Keyword(s):  
Structure Activity Relationships ◽  
Structure Activity

Structure-Activity Relationships in Cannabinoids: An Overview

1987 ◽  
Author(s):  
Raj K. Razdan ◽  
Keyword(s):  
Structure Activity Relationships ◽  
Structure Activity
Sign in / Sign up

Export Citation Format

Share Document