scholarly journals Synthesis and biological evaluation of novel neoflavonoid derivatives as potential antidiabetic agents

RSC Advances ◽  
2017 ◽  
Vol 7 (55) ◽  
pp. 34448-34460 ◽  
Author(s):  
Bing Wang ◽  
Na Li ◽  
Teng Liu ◽  
Jie Sun ◽  
Xiaojing Wang

Various substituted neoflavonoid derivatives were synthesized. These neoflavonoid derivatives were screened for antioxidant, a-glucosidase inhibitory, ALR2 inhibitory and advanced glycation end-product formation inhibitory activities.

MedChemComm ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 545-553 ◽  
Author(s):  
David Cousin ◽  
Marc G. Hummersone ◽  
Tracey D. Bradshaw ◽  
Jihong Zhang ◽  
Christopher J. Moody ◽  
...  

The synthesis and biological evaluation of imidazotetrazines substituted at N-3 is described.


2020 ◽  
Vol 11 (6) ◽  
pp. 5396-5408
Author(s):  
Qian Wu ◽  
Shimiao Tang ◽  
Liang Zhang ◽  
Jinsong Xiao ◽  
Qing Luo ◽  
...  

Catechin has a good inhibitory effect on advanced glycation end product (AGE) formation in alcoholic media, which is generated by Maillard reaction is closely related to diabetes.


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