Synthetic strategies and biomedical applications of I–III–VI ternary quantum dots

2017 ◽  
Vol 5 (31) ◽  
pp. 6193-6216 ◽  
Author(s):  
Wubshet Mekonnen Girma ◽  
Mochamad Zakki Fahmi ◽  
Adi Permadi ◽  
Mulu Alemayehu Abate ◽  
Jia-Yaw Chang

In this review, we discuss recent advances of I–III–VI QDs with a major focus on synthesis and biomedical applications; advantages include low toxicity and fluorescent tuning in the biological window.

2021 ◽  
Vol 120 ◽  
pp. 111756
Author(s):  
Amirhossein Alaghmandfard ◽  
Omid Sedighi ◽  
Nima Tabatabaei Rezaei ◽  
Amir Abbas Abedini ◽  
Adrine Malek Khachatourian ◽  
...  

2019 ◽  
Vol 29 (6) ◽  
pp. 628-640 ◽  
Author(s):  
Chunyan Zhu ◽  
Zhao Chen ◽  
Shuai Gao ◽  
Ban Leng Goh ◽  
Ismail Bin Samsudin ◽  
...  

2017 ◽  
Vol 1 (4) ◽  
pp. 192-199 ◽  
Author(s):  
Fei Chen ◽  
Weiyin Gao ◽  
Xiaopei Qiu ◽  
Hong Zhang ◽  
Lianhua Liu ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Nayab Azam ◽  
Murtaza Najabat Ali ◽  
Tooba Javaid Khan

Carbon quantum dots (CQDs) are a new type of nano-carbons that are currently favored over semiconductor quantum dots (QDs) because of their solubility, low toxicity, eco-friendliness, and cheap and facile synthesis giving desired optical characteristics. Moreover, their physiochemical properties can be controlled by their synthetic route. CQDs can emit fluorescence in the range from the UV to the near-infrared (NIR) region, making them suitable for biomedical applications. Fluorescence in these nano-carbon atoms can be tuned by varying the excitation wavelength. As of now, CQDs have been used in various applications such as in bioimaging, biosensing, electrochemical biosensing, drug delivery, gene delivery, photodynamic therapy in the treatment of cancers, pharmaceutical formulations, and treating inflammation. This article highlights the current progress and advancement of CQDs with focus on their synthetic routes, chemical and optical properties, and biomedical applications along with new perceptions in this interesting and promising field.


2021 ◽  
Author(s):  
Yuhang Miao ◽  
Xiaojing Wang ◽  
Jie Sun ◽  
Zhong Yan

Zero-dimensional (0D) black phosphorus quantum dots (BPQDs), the new derivatives of black phosphorus (BP) nanomaterials, have attracted considerable attention since they were first prepared in 2015.


Molecules ◽  
2021 ◽  
Vol 26 (18) ◽  
pp. 5705
Author(s):  
Leonid L. Fershtat ◽  
Egor S. Zhilin

Nitric oxide (NO) is a key signaling molecule that acts in various physiological processes such as cellular metabolism, vasodilation and transmission of nerve impulses. A wide number of vascular diseases as well as various immune and neurodegenerative disorders were found to be directly associated with a disruption of NO production in living organisms. These issues justify a constant search of novel NO-donors with improved pharmacokinetic profiles and prolonged action. In a series of known structural classes capable of NO release, heterocyclic NO-donors are of special importance due to their increased hydrolytic stability and low toxicity. It is no wonder that synthetic and biochemical investigations of heterocyclic NO-donors have emerged significantly in recent years. In this review, we summarized recent advances in the synthesis, reactivity and biomedical applications of promising heterocyclic NO-donors (furoxans, sydnone imines, pyridazine dioxides, azasydnones). The synthetic potential of each heterocyclic system along with biochemical mechanisms of action are emphasized.


2018 ◽  
Vol 48 (2) ◽  
pp. 209-214 ◽  
Author(s):  
Jae Seo Lee ◽  
Yun Hee Youn ◽  
Il Keun Kwon ◽  
Na Re Ko

2020 ◽  
Author(s):  
Morteza Javadi ◽  
Van A. Ortega ◽  
Alyxandra Thiessen ◽  
Maryam Aghajamali ◽  
Muhammad Amirul Islam ◽  
...  

<p>The design and fabrication of Si-based multi-functional nanomaterials for biological and biomedical applications is an active area of research. The potential benefits of using Si-based nanomaterials are not only due to their size/surface-dependent optical responses but also the high biocompatibility and low-toxicity of silicon itself. Combining these characteristics with the magnetic properties of Fe<sub>3</sub>O<sub>4</sub> nanoparticles (NPs) multiplies the options available for real-world applications. In the current study, biocompatible magnetofluorescent nano-hybrids have been prepared by covalent linking of Si quantum dots to water-dispersible Fe<sub>3</sub>O<sub>4</sub> NPs <i>via</i> dicyclohexylcarbodiimide (DCC) coupling. We explore some of the properties of these magnetofluorescent nano-hybrids as well as evaluate uptake, the potential for cellular toxicity, and the induction of acute cellular oxidative stress in a mast cells-like cell line (RBL-2H3) by heat induction through short-term radio frequency modulation (10 min @ 156 kHz, 500 A). We found that the NPs were internalized readily by the cells and also penetrated the nuclear membrane. Radio frequency activated nano-hybrids also had significantly increased cell death where > 50% of the RBL-2H3 cells were found to be in an apoptotic or necrotic state, and that this was attributable to increased triggering of oxidative cell stress mechanisms. </p>


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