Determination of thermal degradants in e-cigarette fluid via direct sample introduction (DSI) gas chromatography-tandem mass spectrometry

2018 ◽  
Vol 10 (45) ◽  
pp. 5439-5446
Author(s):  
Kevin J. Bisceglia ◽  
Sahar Caravan ◽  
Keegan Rogers ◽  
Ling Huang
Keyword(s):  
Mass Spectrometry ◽  
Electronic Cigarettes ◽  
Sample Introduction ◽  
Tandem Mass ◽  
Tobacco Products ◽  
Chromatography Tandem Mass Spectrometry ◽  
Nicotine Consumption ◽  
Perceived Harm ◽  
Direct Sample

Electronic cigarettes (EC) and other electronic nicotine delivery systems (ENDS) have recently become popular choices for nicotine consumption due to the lower perceived harm compared to conventional tobacco products.

scholarly journals Analysis of Pesticide Residues in Mixed Fruit and Vegetable Extracts by Direct Sample Introduction/Gas Chromatography/Tandem Mass Spectrometry

2000 ◽  
Vol 83 (3) ◽  
pp. 680-697 ◽  
Author(s):  
Steven J Lehotay
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Tandem Mass Spectrometry ◽  
Pesticide Residues ◽  
Sample Introduction ◽  
Breakdown Product ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Relative Standard ◽  
Direct Sample

Abstract Direct sample introduction (DSI), or “dirty sample injection,” was investigated in the determination of 22 diverse pesticide residues in mixed apple, green bean, and carrot extracts by benchtop gas chromatography/tandem mass spectrometry (DSI/GC/MS–MS). The targeted pesticides, some of which were incurred in the samples, included chlorpyrifos, azinphos-methyl, parathion-methyl, diazinon, terbufos, p,p′-DDE, endosulfan sulfate, carbofuran, carbaryl, propargite, bifenthrin, dacthal, trifluralin, metalaxyl, pendimethalin, atrazine, piperonyl butoxide, diphenylamine, vinclozolin, chlorothalonil, quintozene, and tetrahydrophthalimide (the breakdown product of captan). The analytical DSI method entailed the following steps: (1) blend 30 g sample with 60 mL acetonitrile for 1 min in a centrifuge bottle; (2) add 6 g NaCl and blend 30 s; (3) centrifuge for 1–2 min; (4) add 5 mL upper layer to 1 g anhydrous MgSO4 in a vial; and (5) analyze 11 μL extract, using DSI/GC/MS–MS. Sample cleanup is not needed because GC/MS–MS is exceptionally selective for the targeted analytes, and nonvolatile coextracted matrix components do not contaminate the injector or the GC/MS–MS system. Average recoveries of the pesticides were 103 ± s7% with relative standard deviations of 14 ± 5% on average, and limits of detection were <2 ng/g for nearly all pesticides studied. The DSI/GC/MS–MS approach for targeted pesticides is quantitative, confirmatory, sensitive, selective, rugged, rapid, simple, and inexpensive.

Use of a gas-tight syringe sampling method for the determination of tobacco-specific nitrosamines in E-cigarette aerosols by liquid chromatography-tandem mass spectrometry

2015 ◽  
Vol 7 (11) ◽  
pp. 4472-4480 ◽  
Author(s):  
Young-Hwan Cho ◽  
Ho-Sang Shin
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Sampling Method ◽  
Electronic Cigarettes ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Tobacco Specific Nitrosamines ◽  
Gas Tight

We report here a sampling method using a gas-tight syringe (GTS) in the determination of tobacco-specific nitrosamines (TSNAs) in aerosols from electronic cigarettes.

Sign in / Sign up

Export Citation Format

Share Document