A two-photon endoplasmic reticulum-targeting fluorescent probe for the imaging of pH in living cells and zebrafish

2018 ◽  
Vol 10 (47) ◽  
pp. 5702-5706 ◽  
Author(s):  
Nan Zhang ◽  
Baoli Dong ◽  
Xiuqi Kong ◽  
Wenhui Song ◽  
Weiying Lin
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Ph Changes ◽  
Two Photon ◽  
Endoplasmic Reticulum Targeting

The pH changes of the endoplasmic reticulum (ER) are closely related to many diseases.

Development of an endoplasmic reticulum-targeting fluorescent probe for the two-photon imaging of hypochlorous acid (HClO) in living cells

2019 ◽  
Vol 11 (35) ◽  
pp. 4450-4455 ◽  
Author(s):  
Wenhui Song ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Xiuqi Kong ◽  
Abdul Hadi Mehmood ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Endoplasmic Reticulum ◽  
Cell Death ◽  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Living Cells ◽  
Oxygen Species ◽  
Cell Dysfunction ◽  
Two Photon ◽  
Endoplasmic Reticulum Targeting

As an important reactive oxygen species, hypochlorous acid (HClO) could irreversibly destroy Ca2+-ATPase to inhibit Ca2+ transport in the endoplasmic reticulum (ER), which may eventually lead to cell dysfunction and cell death.

An endoplasmic reticulum-targeting and ratiometric fluorescent probe for hypochlorous acid in living cells based on a 1,8-naphthalimide derivative

2020 ◽  
Vol 44 (42) ◽  
pp. 18389-18398
Author(s):  
Qiujuan Ma ◽  
Chunyan Wang ◽  
Guojiang Mao ◽  
Meiju Tian ◽  
Jingguo Sun ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Living Cells ◽  
Endoplasmic Reticulum Targeting ◽  
Ratiometric Fluorescent Probe

A novel reticulum-targeting and ratiometric fluorescent probe for determining hypochlorous acid has been developed.

A tumor-targeting and lysosome-specific two-photon fluorescent probe for imaging pH changes in living cells

2017 ◽  
Vol 5 (5) ◽  
pp. 988-995 ◽  
Author(s):  
Baoli Dong ◽  
Xuezhen Song ◽  
Xiuqi Kong ◽  
Chao Wang ◽  
Nan Zhang ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Fluorescent Probe ◽  
Tumor Targeting ◽  
Living Cells ◽  
Lysosomal Ph ◽  
Ph Changes ◽  
Two Photon

Lysosomal pH is closely related to the metastasis and apoptosis of cancer cells.

A mitochondria-targeted two-photon fluorescent probe for sensing and imaging pH changes in living cells

2020 ◽  
Vol 224 ◽  
pp. 117435 ◽  
Author(s):  
Xueqin Jiang ◽  
Zengjin Liu ◽  
Youzhe Yang ◽  
Hao Li ◽  
Xiaoyi Qi ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Ph Changes ◽  
Two Photon

An endoplasmic reticulum-targeting fluorescent probe for the imaging of GSH in living cells

2019 ◽  
Vol 11 (29) ◽  
pp. 3736-3740 ◽  
Author(s):  
Cheng-Shi Jiang ◽  
Zhi-Qiang Cheng ◽  
Yong-Xi Ge ◽  
Jia-Li Song ◽  
Juan Zhang ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Er Targeting ◽  
Endoplasmic Reticulum Targeting

A new endoplasmic reticulum (ER)-targeting fluorescent probe (ER-G) was designed and applied for the detection of cellular GSH in the ER.

The development of an endoplasmic reticulum-targeting fluorescent probe for the imaging of 1,4-dithiothreitol (DTT) in living cells

2021 ◽  
Author(s):  
Abdul Hadi Mehmood ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Wenhui Song ◽  
Yaru Sun ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Turn On ◽  
Er Targeting ◽  
Endoplasmic Reticulum Targeting ◽  
First Time

An effective turn-on ER-targeting fluorescent probe ER-DTT was designed to image DTT of endoplasmic reticulum for the first time.

Development of an endoplasmic reticulum-targeting fluorescent probe for the imaging of polarity in living cells and tissues

2019 ◽  
Vol 43 (30) ◽  
pp. 12103-12108 ◽  
Author(s):  
Wenhui Song ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Xiuqi Kong ◽  
Abdul Hadi Mehmood ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probe ◽  
Cell Polarity ◽  
Living Cells ◽  
Endoplasmic Reticulum Targeting

Cell polarity is one of the important parameters of the biological microenvironment, and controls the synthesis of functional proteins.

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